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NCT04065516: ARAT
ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia
NA trial testing ARAT technique in Achalasia in 44 participants. Enrolling by invitation.
1 July 2026
Quick facts
| Lead sponsor | Coordinación de Investigación en Salud, Mexico |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 44 |
| Start date | 3 July 2019 |
| Primary completion | 1 July 2026 |
| Estimated completion | 1 December 2026 |
| Sites | 1 location across Mexico |
Drugs / interventions tested
- ARAT technique
Conditions studied
- Achalasia — all drugs for Achalasia →
- Gastroesophageal Reflux — all drugs for Gastroesophageal Reflux →
Sponsor
Coordinación de Investigación en Salud, Mexico — full company profile →
Who can join
18 and older, any sex, with Achalasia or Gastroesophageal Reflux. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The peroral endoscopic myotomy for the treatment of achalasia is associated with a higher incidence of gastroesophageal reflux disease compared with Heller's myotomy. Remodeling of the esophagogastric junction with hybrid argon plasma could decrease the passage of gastric or gastroduodenal content into the esophagus.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04065516
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Achalasia
Currently open trials in the same condition.
- NCT07496840 — Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM) · recruiting
- NCT07406945 — Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM · NA · recruiting
- NCT06042127 — POEM-F for Achalasia International Study · NA · recruiting
- NCT05772260 — Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy · recruiting
- NCT07181070 — The Use of Indocyanine Green Fluorescence (ICG) During Laparoscopic Heller- Dor · recruiting
Other Coordinación de Investigación en Salud, Mexico trials
Trials by the same sponsor.
- NCT07248813 — Telerehabilitation Program to Improve Function in People With Chronic Low Back Pain Compared With Conventional Care · NA · recruiting
- NCT07248891 — Type 2 Diabetes and Associated Factors in Mexico · enrolling by invitation
- NCT06847373 — Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity · NA · recruiting
- NCT07248761 — Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri · Phase 4 · active not recruiting
- NCT06782737 — Mediterranean Diet Versus Standard Diet on Candiormetabolic Indicator in Patients With Apnea · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04065516 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Coordinación de Investigación en Salud, Mexico
- Last refreshed: 25 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04065516.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing