NCT04056884: SIBS-RCT

SIBS-Intervention for Siblings and Parents of Children With Chronic Illness

Completed NA Last updated 16 September 2025

What this trial tests

NA trial testing SIBS intervention in Siblings of Children With Chronic Illness in 288 participants. Completed in 30 September 2024.

Timeline

1 September 2019

Primary endpoint
30 September 2023

30 September 2024

Quick facts

Lead sponsor	University of Oslo
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	prevention
Enrollment	288
Start date	1 September 2019
Primary completion	30 September 2023
Estimated completion	30 September 2024
Sites	1 location across Norway

Drugs / interventions tested

• SIBS intervention

Conditions studied

• Siblings of Children With Chronic Illness — all drugs for Siblings of Children With Chronic Illness →

Sponsor

University of Oslo

Who can join

Adults 8 to 16, any sex, with Siblings of Children With Chronic Illness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

SIBS-RCT is a randomized controlled trial comparing the effect of a 5-session group intervention for siblings and parents of children with chronic illness to 12-week waitlist. Participants randomized to waitlist will receive the intervention after waitlist. The main outcome is sibling mental health, and secondary outcomes include family communication, sibling disorder knowledge, quality of life, and adaption. Outcomes will be examined at pre-, post, 3-, 6- and 12- month follow-up.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

1. Group intervention for siblings and parents of children with chronic disorders (SIBS-RCT): study protocol for a randomized controlled trial.
   Fjermestad KW, Silverman WK, Vatne TM. · · 2020 · cited 16× · PMID 33054825 · DOI 10.1186/s13063-020-04781-6
2. Measuring adjustment of siblings of children with disabilities: psychometric properties across translations, age groups and informants.
   Veerman LKM, Orm S, Fjermestad KW, Vatne TM, et al · · 2025 · cited 4× · PMID 39882423 · DOI 10.1080/20473869.2024.2411511
3. Effectiveness of a group intervention to improve mental health in siblings of children with chronic disorders: a cluster randomized controlled trial.
   Kirchhofer SM, Fredriksen T, Orm S, Botta M, et al · · 2025 · cited 3× · PMID 40146207 · DOI 10.1093/jpepsy/jsaf021
4. "It's like a car that doesn't like gasoline" - a qualitative study of siblings' understanding of anorexia nervosa in childhood: perspectives from siblings and parents.
   Schumann A, Vatne TM, Dalton L, Rapa E, et al · · 2025 · PMID 41121407 · DOI 10.1186/s40337-025-01263-5