Who is sponsoring NCT04047693?

NCT04047693 is sponsored by Pusan National University Yangsan Hospital.

What drugs are being tested in NCT04047693?

Interventions in NCT04047693: dose dense MVAC with pegylated GCSF.

What condition does NCT04047693 study?

NCT04047693 studies Muscle Invasive Bladder Cancer, Urothelial Carcinoma, Neoadjuvant Chemotherapy.

Is NCT04047693 still recruiting?

NCT04047693 is currently status unknown. Last updated 18 February 2022.

Last reviewed 2022-02-18 · How we verify

NCT04047693

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Status unknown Phase 2 Last updated 18 February 2022

What this trial tests

Phase 2 trial testing dose dense MVAC with pegylated GCSF in Muscle Invasive Bladder Cancer in 32 participants. Status unknown.

Timeline

1 May 2019

Primary endpoint
31 January 2022

31 October 2022

Quick facts

Lead sponsor	Pusan National University Yangsan Hospital
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	32
Start date	1 May 2019
Primary completion	31 January 2022
Estimated completion	31 October 2022
Sites	1 location across South Korea

Drugs / interventions tested

dose dense MVAC with pegylated GCSF — full drug profile →

Conditions studied

Muscle Invasive Bladder Cancer — all drugs for Muscle Invasive Bladder Cancer →
Urothelial Carcinoma — all drugs for Urothelial Carcinoma →
Neoadjuvant Chemotherapy — all drugs for Neoadjuvant Chemotherapy →

Sponsor

Pusan National University Yangsan Hospital

Who can join

18 and older, any sex, with Muscle Invasive Bladder Cancer or Urothelial Carcinoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective is to investigate the efficacy and safety of four cycles of ddMVAC with G-CSF support in patients with MIBC and locally advanced UC

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Bladder Cancer: Current Challenges and Future Directions.
Dobruch J, Oszczudłowski M. · · 2021 · cited 280× · PMID 34440955 · DOI 10.3390/medicina57080749
Neoadjuvant Treatment in Muscle-Invasive Bladder Cancer: From the Beginning to the Latest Developments.
Roviello G, Catalano M, Santi R, Santoni M, et al · · 2022 · cited 18× · PMID 35936721 · DOI 10.3389/fonc.2022.912699
[Locally advanced or oligometastatic bladder cancer-role of local treatment of the primary tumor and metastases].
Rebhan K, Gust KM. · · 2021 · PMID 34825935 · DOI 10.1007/s00120-021-01712-4

Verify or expand the search:

Other recruiting trials for Muscle Invasive Bladder Cancer

Currently open trials in the same condition.

NCT07202819 — Effect of Neoadjuvant Chemotherapy on MRI Accuracy Before Cystectomy · NA · recruiting
NCT06916494 — Pilot Study on Rutin Combined With Tislelizumab and GC (Gemcitabine and Cisplatin) as Neoadjuvant Therapy for Platinum-r · Phase 1 · recruiting
NCT04960709 — Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patient · Phase 3 · active not recruiting
NCT03732677 — Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC · Phase 3 · active not recruiting
NCT02546661 — Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer · Phase 1 · active not recruiting

Other Pusan National University Yangsan Hospital trials

Trials by the same sponsor.

NCT07511634 — Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Cont · NA · not yet recruiting
NCT07324226 — Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adul · NA · recruiting
NCT07334327 — Extracorporeal Blood Purification Using Oxiris for Septic Shock (EXPLORE Study) · NA · not yet recruiting
NCT07323823 — The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients · NA · not yet recruiting
NCT07447271 — Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04047693 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Pusan National University Yangsan Hospital
Last refreshed: 18 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04047693.

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