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NCT04045444: OXYSENIOR
Cerebral Oxygenation During Gait in Elderly
NA trial testing walking in Cerebral Oxygenation in 117 participants. Completed in 20 April 2021.
20 April 2021
Quick facts
| Lead sponsor | Centre Hospitalier Régional d'Orléans |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 117 |
| Start date | 25 February 2019 |
| Primary completion | 20 April 2021 |
| Estimated completion | 20 April 2021 |
| Sites | 1 location across France |
Drugs / interventions tested
- walking
- cognitive task
Conditions studied
- Cerebral Oxygenation — all drugs for Cerebral Oxygenation →
Sponsor
Centre Hospitalier Régional d'Orléans
Who can join
Adults 18 to 30, any sex, with Cerebral Oxygenation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ageing is accompanied by a cognitive decline altering gait and increasing the risk of falling. Physical activity could reduce this cognitive decline by an improvement in the oxygen supply to the brain. At the moment, the effect of physical activity on brain oxygenation during walking in elderly has never been described. Moreover, the increase in cognitive request during a dual task could lead to an increase in the risk of falling. In this context, the investigators of Orleans's hospital want to examine the effect of the physical activity level of elderly on their brain oxygenation during walking and during a dual task. Moreover, Parkinson' patients could display an impairment of gait and cognitive function. Attentional task and dual task situation are particularly impaired in this pathology. This is why the investigators of Orleans's hospital want to also examine cerebral activation of these patients during walking and during a dual task. The hemodynamic cerebral activation will be studied using the near infrared spectroscopy at the level of the prefrontal cortex. This non-invasive technic allows the evaluation of the regional oxyhemoglobin and deoxyhemoglobin variations induced by cerebral activation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04045444
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Cerebral Oxygenation
Currently open trials in the same condition.
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- NCT07270341 — Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anest · recruiting
- NCT04722939 — Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury · recruiting
Other Centre Hospitalier Régional d'Orléans trials
Trials by the same sponsor.
- NCT07522307 — Psychological Impact of an 80-km Ultra-Endurance Race · recruiting
- NCT07522333 — Psychological Impact of an 120-km Ultra-Endurance Race · recruiting
- NCT07334964 — Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method · NA · recruiting
- NCT07203807 — Study of the Optimal Number of Repetitions to Investigate the Cerebral Activity by fNIRS During a Voluntary Movement and · completed
- NCT07305701 — Cohort Study on Medical Students' Mental Health · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04045444 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Régional d'Orléans
- Last refreshed: 1 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04045444.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing