NCT04044924 (GREAT-STOP) is a clinical trial in Head Injury, sponsored by Florida Atlantic University.

Who is sponsoring NCT04044924?

NCT04044924 is sponsored by Florida Atlantic University.

What condition does NCT04044924 study?

NCT04044924 studies Head Injury, Anticoagulant-induced Bleeding, Fall.

Is NCT04044924 still recruiting?

NCT04044924 is currently completed. Last updated 3 August 2022.

Last reviewed 2022-08-03 · How we verify

NCT04044924: GREAT-STOP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Geriatric Head Trauma Short Term Outcomes Project

Completed Last updated 3 August 2022

What this trial tests

trial in Head Injury in 5,387 participants. Completed in 14 November 2020.

Timeline

15 August 2019

Primary endpoint
14 November 2020

14 November 2020

Quick facts

Lead sponsor	Florida Atlantic University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	5,387
Start date	15 August 2019
Primary completion	14 November 2020
Estimated completion	14 November 2020
Sites	2 locations across United States

Conditions studied

Head Injury — all drugs for Head Injury →
Anticoagulant-induced Bleeding — all drugs for Anticoagulant-induced Bleeding →
Fall — all drugs for Fall →

Sponsor

Florida Atlantic University

Who can join

65 and older, any sex, with Head Injury or Anticoagulant-induced Bleeding. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective observational study will examine the incidence of intracranial hemorrhage. The investigators will compare patients on anticoagulant and/or antiplatelet therapy with head trauma compared to patients not on these medications. While many studies have sought to quantify the incidence of intracranial hemorrhage in these patients, there is considerable controversy regarding their care and what to do after an initial negative head CT in anticoagulated geriatric patients who have experienced head trauma.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Alcohol use is associated with intracranial hemorrhage in older emergency department head trauma patients.
Zirulnik A, Liu S, Wells M, Alter SM, et al · · 2024 · cited 3× · PMID 39086794 · DOI 10.1002/emp2.13245

Verify or expand the search:

Other recruiting trials for Head Injury

Currently open trials in the same condition.

NCT07111871 — Healthcare Services for Older People Who Have Fallen With Potential Head Injury · recruiting
NCT05562050 — Characteristics of the Anosmic Olfactory Mucosa · active not recruiting
NCT05622461 — Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery · NA · recruiting
NCT07195760 — Delayed IntraCranial Hemorrhage in Oral AntiCoagulant Treated Patients With Mild Traumatic Brain Injury · active not recruiting
NCT05364749 — Selective CT for Anticoagulated Head Injured Patients · recruiting

Other Florida Atlantic University trials

Trials by the same sponsor.

NCT06645548 — Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency · NA · withdrawn
NCT06646133 — Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency · withdrawn
NCT07127510 — Brain NAD in Alzheimer's Disease · recruiting
NCT07587957 — Exploring the Feasibility of an Exercise and Noninvasive Brain Stimulation Intervention in Breast Cancer Survivors · NA · recruiting
NCT07216846 — The Geriatric Emergency Department Pharmacologic Harm Prevention Project · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04044924 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Florida Atlantic University
Last refreshed: 3 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04044924.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing