NCT04041817: Trigger

Pulmonary and Ventilatory Effects of Trigger Modulation in Intubated ICU

Completed NA Last updated 17 February 2023

What this trial tests

NA trial testing Trigger setting of pressure support ventilation in ICU Patients in 30 participants. Completed in 31 January 2023.

Timeline

3 April 2019

Primary endpoint
31 January 2023

31 January 2023

Quick facts

Lead sponsor	University Hospital, Clermont-Ferrand
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	3 April 2019
Primary completion	31 January 2023
Estimated completion	31 January 2023
Sites	1 location across France

Drugs / interventions tested

• Trigger setting of pressure support ventilation

Conditions studied

• ICU Patients — all drugs for ICU Patients →
• Intubation — all drugs for Intubation →
• Spontaneously Breathing — all drugs for Spontaneously Breathing →
• Pulmonary Function — all drugs for Pulmonary Function →

Sponsor

University Hospital, Clermont-Ferrand

Who can join

18 and older, any sex, with ICU Patients or Intubation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pressure support ventilation allows intubated ICU patients to breathe spontaneously. Among specific settings, the adjustment of the trigger value (or threshold for triggering the ventilator) has not been explored to date. The trigger threshold corresponds to the sensitivity of the ventilator to detect patient's inspiratory effort and then deliver the predefined pressure support to inflate the lungs and deliver a tidal volume. The purpose of this study is to explore the influence of trigger level on pulmonary and ventilatory physio (-patho)logical parameters in spontaneously breathing ICU patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.