Who is sponsoring NCT04038814?

NCT04038814 is sponsored by Andrzej Frycz Modrzewski Krakow University.

What drugs are being tested in NCT04038814?

Interventions in NCT04038814: Routine prevention of VAP, Modified prevention of VAP.

What condition does NCT04038814 study?

NCT04038814 studies VAP - Ventilator Associated Pneumonia.

Is NCT04038814 still recruiting?

NCT04038814 is currently completed. Last updated 31 July 2019.

Last reviewed 2019-07-31 · How we verify

NCT04038814: VAP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effectiveness of the Modified Bundle in the Prevention of VAP.

Completed Last updated 31 July 2019

What this trial tests

trial testing Routine prevention of VAP in VAP - Ventilator Associated Pneumonia in 386 participants. Completed in 15 July 2019.

Timeline

1 June 2018

Primary endpoint
1 July 2019

15 July 2019

Quick facts

Lead sponsor	Andrzej Frycz Modrzewski Krakow University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	386
Start date	1 June 2018
Primary completion	1 July 2019
Estimated completion	15 July 2019
Sites	1 location across Poland

Drugs / interventions tested

Routine prevention of VAP
Modified prevention of VAP

Conditions studied

VAP - Ventilator Associated Pneumonia — all drugs for VAP - Ventilator Associated Pneumonia →

Sponsor

Andrzej Frycz Modrzewski Krakow University

Who can join

18 and older, any sex, with VAP - Ventilator Associated Pneumonia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ventilator-associated pneumonia (VAP) is an important cause of prolonged intensive care unit and hospital length of stay, healthcare costs and mortality in mechanically ventilated patients. There are an international guidelines for VAP diagnosis, treatment and prevention (Infectious Diseases Society of America(IDSA)/American Thoracic Society (ATS) 2016 and European Respiratory Society (ERS) / European Society of Intensive Care Medicine (ESICM) / European Society of Clinical Microbiology and Infectiuos Diseases (ESCMID) / Asociacion Latinoamericana del Torax (ALAT) 2017) routinely used in most ICUs. The investigator planed on comparing two strategies for prevention of VAP in mechanically ventilated patients: the routine VAP bundle ( historical group - VAP1) and the modified VAP bundle ( study group - VAP2) by using 3 modifications ( Shiley Evac Endotracheal tube with TaperGuard Cuff, Automatic continuous subglottic secretion drainage (SSD) and continuous tube cuff pressure monitoring). The aim of the study is an assessment of the effectiveness of the modified prevention of VAP in reduction of: early and late VAP cases, mechanical ventilation days (MV), length of stay (LOS) in the ICU, 28 day mortality and multi drug resistent pathogens (MDR) cases in adult ICU patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Risk Factors and Protective Factors against Ventilator-Associated Pneumonia-A Single-Center Mixed Prospective and Retrospective Cohort Study.
Pawlik J, Tomaszek L, Mazurek H, Mędrzycka-Dąbrowska W. · · 2022 · cited 14× · PMID 35455713 · DOI 10.3390/jpm12040597
Automatic Continuous Control of Cuff Pressure and Subglottic Secretion Suction Used Together to Prevent Pneumonia in Ventilated Patients-A Retrospective and Prospective Cohort Study.
Tomaszek L, Pawlik J, Mazurek H, Mędrzycka-Dąbrowska W. · · 2021 · cited 3× · PMID 34768471 · DOI 10.3390/jcm10214952

Verify or expand the search:

Other recruiting trials for VAP - Ventilator Associated Pneumonia

Currently open trials in the same condition.

NCT06662630 — Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in Mechanical Ventilation Patients · NA · recruiting
NCT05952648 — HAP/VAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array · NA · recruiting

Other Andrzej Frycz Modrzewski Krakow University trials

Trials by the same sponsor.

NCT06849297 — Effectiveness of Aromatherapy in Reducing Anxiety and Pain Perception in Women During Childbirth · NA · active not recruiting
NCT06976463 — Parental Knowledge of First Aid for Choking and Cardiopulmonary Resuscitation in Infants Under One Year of Age · recruiting
NCT06148116 — Attitudes and Knowledge of Dialysis Patients Towards Kidney Transplantation · unknown
NCT06395831 — Assessment of Quality of Life and Independence, as Well as Received Social Support for Spinal Cancer. · recruiting
NCT06395805 — Evaluation of Quality of Life and Self-assurance and Social Support Earned for Non-cellular Head Cancer · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04038814 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Andrzej Frycz Modrzewski Krakow University
Last refreshed: 31 July 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04038814.

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