NCT04030780 is a NA clinical trial of spore-forming probiotic in Dyspepsia, sponsored by Universitaire Ziekenhuizen KU Leuven.

Who is sponsoring NCT04030780?

NCT04030780 is sponsored by Universitaire Ziekenhuizen KU Leuven.

What drugs are being tested in NCT04030780?

Interventions in NCT04030780: spore-forming probiotic, Placebo.

What condition does NCT04030780 study?

NCT04030780 studies Dyspepsia, Dysbiosis.

Is NCT04030780 still recruiting?

NCT04030780 is currently completed. Last updated 16 February 2021.

Last reviewed 2021-02-16 · How we verify

NCT04030780

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Sporebiotics in FD

Completed NA Last updated 16 February 2021

What this trial tests

NA trial testing spore-forming probiotic in Dyspepsia in 60 participants. Completed in 31 December 2020.

Timeline

3 June 2019

Primary endpoint
7 July 2020

31 December 2020

Quick facts

Lead sponsor	Universitaire Ziekenhuizen KU Leuven
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	60
Start date	3 June 2019
Primary completion	7 July 2020
Estimated completion	31 December 2020
Sites	1 location across Belgium

Drugs / interventions tested

spore-forming probiotic
Placebo

Conditions studied

Dyspepsia — all drugs for Dyspepsia →
Dysbiosis — all drugs for Dysbiosis →

Sponsor

Universitaire Ziekenhuizen KU Leuven — full company profile →

Who can join

Adults 18 to 99, any sex, with Dyspepsia or Dysbiosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Single-site prospective interventional study aiming to demonstrate the effect of spore-forming probiotics on dyspeptic symptoms and blood, saliva and stool parameters in FD patients with and without acid suppression, compared to placebo.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial.
Wauters L, Slaets H, De Paepe K, Ceulemans M, et al · · 2021 · cited 66× · PMID 34358486 · DOI 10.1016/s2468-1253(21)00226-0
Recent advances in therapeutic probiotics: insights from human trials.
Cho M-Y, Eom J-H, Choi E-M, Yang S-J, et al · · 2025 · cited 17× · PMID 40261032 · DOI 10.1128/cmr.00240-24

Verify or expand the search:

Other recruiting trials for Dyspepsia

Currently open trials in the same condition.

NCT06941545 — High Resolution Gastric Mapping and Gastroduodenal Manometry · NA · recruiting
NCT07261228 — The Difference in Carbon Footprint Between Diagnostic Upper GI Endoscopy in Dyspeptic Patients Versus Therapeutic Upper · recruiting
NCT06755671 — A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms · recruiting
NCT06422052 — Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspep · recruiting
NCT05810168 — Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia · NA · recruiting

Other Universitaire Ziekenhuizen KU Leuven trials

Trials by the same sponsor.

NCT06831955 — LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer · Phase 2 · recruiting
NCT07356505 — Efficacy and Safety of Micra AV2 Transcatheter Pacing System · NA · recruiting
NCT07286968 — Gastro-Intestinal Digestion and Physiology After Bariatric Surgery · recruiting
NCT06962137 — Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer · Phase 2 · recruiting
NCT07270536 — Accelerated Pacing and Cardiac Filling Pressures During Exercise in Patients With Heart Failure With Preserved Ejection · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04030780 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitaire Ziekenhuizen KU Leuven
Last refreshed: 16 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04030780.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing