NCT04028310: DDMR

Developmental Dyslexia and Remediation Methods

Completed NA Last updated 29 September 2023

What this trial tests

NA trial testing Phonological in Dyslexia, Developmental in 145 participants. Completed in 12 December 2022.

Timeline

25 October 2019

Primary endpoint
12 December 2022

12 December 2022

Quick facts

Lead sponsor	Fondation Lenval
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	other
Enrollment	145
Start date	25 October 2019
Primary completion	12 December 2022
Estimated completion	12 December 2022
Sites	1 location across France

Drugs / interventions tested

• Phonological
• Visual-attention

Conditions studied

• Dyslexia, Developmental — all drugs for Dyslexia, Developmental →

Sponsor

Fondation Lenval — full company profile →

Who can join

Adults 8 to 13, any sex, with Dyslexia, Developmental. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

At least, three theoretical frameworks are currently involved in therapeutic research in developmental dyslexia. Each theoretical framework relies on the type of underlying cognitive processes that is viewed as impaired: 1°) phonological processing, 2°) cross modal integration, 3°) visual attention processing. In this controlled and randomized study, three types of computerized training are combined in a multi-factorial remedial approach in 8 to 12 year old children with dyslexia. The main objective is to compare the effectiveness of this remedial approach which combines phonological, visual-attentional and cross-modal training with conventional non-intensive and non-specific rehabilitation

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Multimodal intervention in 8- to 13-year-old French dyslexic readers: Study protocol for a randomized multicenter controlled crossover trial.
   Harrar-Eskinazi KL, De Cara B, Leloup G, Nothelier J, et al · · 2022 · cited 2× · PMID 36578007 · DOI 10.1186/s12887-022-03701-8
2. Effects of a developmental dyslexia remediation protocol based on the training of audio-phonological cognitive processes in dyslexic children with high intellectual potential: study protocol for a multiple-baseline single-case experimental design.
   Darrot G, Gros A, Manera V, De Cara B, et al · · 2023 · PMID 37592217 · DOI 10.1186/s12887-023-04189-6