Closed-loop Double-vasopressor Automated System vs Manual Bolus Vasopressor to Treat Hypotension During Spinal Anaesthesia for Caesarean Section

NCT04025918 Phase 2/Phase 3 COMPLETED

Hypotension occurs commonly during spinal anesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive arterial pressure monitoring (CNAP, CNSystems, Austria).

Details

Lead sponsor	KK Women's and Children's Hospital
Phase	Phase 2/Phase 3
Status	COMPLETED
Enrolment	216
Start date	2011-10
Completion	2012-07

Conditions

• Hypotension

Interventions

• Vasopressor automated delivery system
• Phenylephrine
• Ephedrine
• Manual vasopressor delivery system

Primary outcomes

• Hypotension — 1 day
  Incidence of systolic blood pressure less than 80% of baseline systolic blood pressure