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NCT04019314
Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)
NA trial testing Blood Collection in Heart Failure in 20 participants. Completed in 6 October 2021.
6 October 2021
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 20 |
| Start date | 11 June 2019 |
| Primary completion | 6 October 2021 |
| Estimated completion | 6 October 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Blood Collection — full drug profile →
- Blood Volume Analysis
Conditions studied
- Heart Failure — all drugs for Heart Failure →
- Volume Overload — all drugs for Volume Overload →
- Decompensated Heart Failure — all drugs for Decompensated Heart Failure →
- Systolic Heart Failure — all drugs for Systolic Heart Failure →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Heart Failure or Volume Overload. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Researchers are observing the values of proEnkephalin (PENK) via a blood draw in hospitalized patients that are volume overloaded requiring diuresis. If changes in PENK are found, physicians may predict values of change in kidney function during treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04019314
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Heart Failure
Currently open trials in the same condition.
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- NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
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Other Mayo Clinic trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04019314 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 23 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04019314.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing