NCT04018560 is a NA clinical trial of Al-Anon Intensive Referral (AIR) in Alcohol Use Disorder, sponsored by Palo Alto Veterans Institute for Research.

Who is sponsoring NCT04018560?

NCT04018560 is sponsored by Palo Alto Veterans Institute for Research.

What drugs are being tested in NCT04018560?

Interventions in NCT04018560: Al-Anon Intensive Referral (AIR).

What condition does NCT04018560 study?

NCT04018560 studies Alcohol Use Disorder.

Is NCT04018560 still recruiting?

NCT04018560 is currently completed. Last updated 5 May 2021.

Last reviewed 2021-05-05 · How we verify

NCT04018560

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intensive Referral to Al-Anon: Benefits to Concerned Others and Their Drinkers

Completed NA Last updated 5 May 2021

What this trial tests

NA trial testing Al-Anon Intensive Referral (AIR) in Alcohol Use Disorder in 402 participants. Completed in 28 February 2021.

Timeline

7 March 2017

Primary endpoint
1 October 2019

28 February 2021

Quick facts

Lead sponsor	Palo Alto Veterans Institute for Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	health services research
Enrollment	402
Start date	7 March 2017
Primary completion	1 October 2019
Estimated completion	28 February 2021
Sites	1 location across United States

Drugs / interventions tested

Al-Anon Intensive Referral (AIR)

Conditions studied

Alcohol Use Disorder — all drugs for Alcohol Use Disorder →

Sponsor

Palo Alto Veterans Institute for Research

Who can join

19 and older, any sex, with Alcohol Use Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is examining the effectiveness of Al-Anon Intensive Referral (AIR) with Concerned Others (COs) of individuals in treatment for alcohol use disorders ("drinkers"). AIR's goal is to facilitate Al-Anon participation and positive outcomes among COs.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Al-Anon Intensive Referral to facilitate concerned others' participation in Al-Anon Family Groups: a randomized controlled trial.
Timko C, Grant KM, Han X, Young LB, et al · · 2022 · cited 4× · PMID 34427006 · DOI 10.1111/add.15670
Predictors of concerned others' mental health and quality of life over 12 months following adults' entry into treatment for an alcohol use disorder.
Cucciare MA, Han X, Yousef S, Timko C. · · 2024 · cited 1× · PMID 38866140 · DOI 10.1016/j.josat.2024.209434
Patient-Concerned Other Dyads' 12-Step Involvement and Patients' Substance Use: A Latent Class Growth Model Analysis.
Timko C, Cucciare MA, Lor MC, Stein M, et al · · 2023 · cited 1× · PMID 37219032 · DOI 10.15288/jsad.22-00378
Predictors of alcohol use disorder treatment outcomes over 12 months: Role of concerned others' functioning and Al-Anon participation.
Cucciare MA, Han X, Timko C. · · 2022 · cited 1× · PMID 35780624 · DOI 10.1016/j.drugalcdep.2022.109546
Predictors of concerned others' Al-Anon attendance and involvement following adults' entry into treatment for an alcohol use disorder.
Cucciare MA, Han X, Kennedy K, Timko C. · · 2025 · PMID 40415638 · DOI 10.1111/acer.70085

Verify or expand the search:

Other recruiting trials for Alcohol Use Disorder

Currently open trials in the same condition.

NCT06860607 — Environment and Alcohol: A Pilot Study · Phase 1 · recruiting
NCT07325266 — Human Laboratory Study of Apremilast for Alcohol Use Disorder · Phase 2 · recruiting
NCT07046819 — Tirzepatide in MetALD · Phase 2 · recruiting
NCT07279558 — Cannabidiol and Alcohol Use Disorder Phenotypes · Phase 2 · recruiting
NCT07056894 — Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis · NA · recruiting

Other Palo Alto Veterans Institute for Research trials

Trials by the same sponsor.

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NCT07303725 — Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology · recruiting
NCT07303712 — Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04018560 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Palo Alto Veterans Institute for Research
Last refreshed: 5 May 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04018560.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing