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NCT04016948
Optical Biopsy for Distal Margin in Low Rectal Cancer
NA trial testing Probe-based confocal laser endomicroscopy optical biopsy in Rectal Cancer in 146 participants. Status unknown.
1 September 2020
Quick facts
| Lead sponsor | Nanfang Hospital, Southern Medical University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 146 |
| Start date | 28 June 2017 |
| Primary completion | 1 September 2020 |
| Estimated completion | 1 May 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- Probe-based confocal laser endomicroscopy optical biopsy
- Intra-operative frozen section
Conditions studied
- Rectal Cancer — all drugs for Rectal Cancer →
Sponsor
Nanfang Hospital, Southern Medical University
Who can join
Adults 18 to 70, any sex, with Rectal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a multi-center prospective randomized controlled study. In this study, the investigators will use confocal laser endomicroscopy to make real-time in vivo optical biopsy of distal margin in rectal cancer surgery and help surgeons to make surgical decision.The investigators also assess the accuracy of CLE optical biopsy, compared with intra-operative frozen section.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Real-time <i>in vivo</i> distal margin selection using confocal laser endomicroscopy in transanal total mesorectal excision for rectal cancer.
Tan J, Ji HL, Hu YW, Li ZM, et al · · 2022 · cited 1× · PMID 36632126 · DOI 10.4240/wjgs.v14.i12.1375
Verify or expand the search:
- PubMed search for NCT04016948
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Nanfang Hospital, Southern Medical University trials
Trials by the same sponsor.
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- NCT07537777 — Benmelstobart Plus Anlotinib Combined With SBRT for Patients With Hepatocellular Carcinoma Failing First-Line Targeted T · Phase 2 · not yet recruiting
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- NCT07511894 — Beta-Blockers on the Efficacy of Neoadjuvant Immunotherapy for Gastric Cancer · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04016948 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nanfang Hospital, Southern Medical University
- Last refreshed: 12 July 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04016948.
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