NCT04014127 (CRIB-FLOW) is a clinical trial of Coronary flow reserve assessment in Kidney Disease, Chronic, sponsored by University Hospital Birmingham NHS Foundation Trust.

Who is sponsoring NCT04014127?

NCT04014127 is sponsored by University Hospital Birmingham NHS Foundation Trust.

What drugs are being tested in NCT04014127?

Interventions in NCT04014127: Coronary flow reserve assessment, Sphygmocor, Electrocardiogram, Blood test, Urinary albumin/creatinine ratio.

What condition does NCT04014127 study?

NCT04014127 studies Kidney Disease, Chronic, Myocardial Dysfunction.

Is NCT04014127 still recruiting?

NCT04014127 is currently status unknown. Last updated 10 July 2019.

Last reviewed 2019-07-10 · How we verify

NCT04014127: CRIB-FLOW

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Coronary Microvascular Dysfunction in Chronic Kidney Disease

Status unknown Last updated 10 July 2019

What this trial tests

trial testing Coronary flow reserve assessment in Kidney Disease, Chronic in 100 participants. Status unknown.

Timeline

7 May 2019

Primary endpoint
31 August 2020

31 December 2020

Quick facts

Lead sponsor	University Hospital Birmingham NHS Foundation Trust
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	100
Start date	7 May 2019
Primary completion	31 August 2020
Estimated completion	31 December 2020
Sites	1 location across United Kingdom

Drugs / interventions tested

Coronary flow reserve assessment
Sphygmocor
Electrocardiogram
Blood test — full drug profile →
Urinary albumin/creatinine ratio

Conditions studied

Kidney Disease, Chronic — all drugs for Kidney Disease, Chronic →
Myocardial Dysfunction — all drugs for Myocardial Dysfunction →

Sponsor

University Hospital Birmingham NHS Foundation Trust

Who can join

18 and older, any sex, with Kidney Disease, Chronic or Myocardial Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is an observational study assessing coronary microvascular function in healthy controls with normal kidney function, living kidney donors, pre-dialysis patients with chronic kidney disease stage 5 and patients on peritoneal dialysis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Coronary flow velocity reserve and inflammatory markers in living kidney donors.
Radhakrishnan A, Price AM, Pickup LC, Law JP, et al · · 2020 · cited 7× · PMID 32805328 · DOI 10.1016/j.ijcard.2020.08.013

Verify or expand the search:

Other recruiting trials for Kidney Disease, Chronic

Currently open trials in the same condition.

NCT07217535 — Rutgers University Study of the Genetics of Kidney Disease · recruiting
NCT06343727 — A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF) · NA · recruiting
NCT06701825 — Effectiveness and Cost-effectiveness of a Pre-emptive Genotyping Strategy in Patients Receiving Tacrolimus · Phase 4 · recruiting
NCT06830473 — KTRSensor Scotland Study: An Observational Study Into Predictors and Diagnosis of Kidney Transplant Rejection · recruiting
NCT06863194 — Probiotic Supplementation and Disease Progression in CKD: A Randomized Trial · Phase 1, PHASE2 · recruiting

Other University Hospital Birmingham NHS Foundation Trust trials

Trials by the same sponsor.

NCT04916704 — Subclinical Cytomegalovirus Reactivation in Acute ANCA-associated Vasculitis · active not recruiting
NCT05376228 — A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment o · unknown
NCT04727268 — Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa · unknown
NCT05405907 — Evaluation of the Haemostatic Agent Purabond in ENT TORS · completed
NCT04902352 — The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resecta · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04014127 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital Birmingham NHS Foundation Trust
Last refreshed: 10 July 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04014127.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing