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NCT04011072

Far Infrared Therapy on Arteriovenous Fistulas in Hemodialysis Patients

Completed NA Last updated 29 February 2024
What this trial tests

NA trial testing Far infrared radiation in Arterio-venous Fistula in 206 participants. Completed in 29 August 2023.

Timeline
3 October 2019
Primary endpoint
29 August 2023
29 August 2023

Quick facts

Lead sponsorHerlev and Gentofte Hospital
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeprevention
Enrollment206
Start date3 October 2019
Primary completion29 August 2023
Estimated completion29 August 2023
Sites9 locations across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

Herlev and Gentofte Hospital

Who can join

18 and older, any sex, with Arterio-venous Fistula. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The number of hemodialysis patients in the world are increasing. In order to receive a sufficient dialysis, the patients needs a well functioning and stable vascular access - preferably an arteriovenous fistula (AVF). Unfortunately, the AVF has a high incidence of stenosis with percutaneous trans luminal angioplasty (PTA) as the only treatment option and a short lifetime. Little do we know of how to improve the survival of the AVF. With this study we want to explore the effect of far infrared therapy on the stenosis, maturation and survival of the arteriovenous fistula. The investigators will divide the patients into 2 groups: A treatment group and a control group. The treatment group will receive infrared therapy on their fistula during their dialysis session. The control group will not receive any infrared therapy. The investigators hope to reduce the risk of stenosis in the fistula and improve the fistula survival with this treatment. Furthermore, the investigators want to explore the change in several biochemical markers during the treatment with infrared therapy.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Effect of far infrared therapy on arteriovenous fistula maturation, survival and stenosis in hemodialysis patients, a randomized, controlled clinical trial: the FAITH on fistula trial.
    Lindhard K, Rix M, Heaf JG, Hansen HP, et al · · 2021 · cited 10× · PMID 34419006 · DOI 10.1186/s12882-021-02476-x
  2. Cellular and molecular mechanisms underlying hemodialysis arteriovenous fistula dysfunction and approaches to promote maturation: a vascular perspective.
    Shiu YT, Northrup H, Huang Y, Cho ME, et al · · 2025 · cited 7× · PMID 40465509 · DOI 10.1152/ajpheart.00010.2025
  3. The effect of far infrared radiation on maturation in arteriovenous fistulas in patients on hemodialysis: A randomized controlled, multicenter trial.
    Lindhard K, Hansen HP, Gliese K, Hansen E, et al · · 2026 · PMID 41178583 · DOI 10.1177/11297298251385043

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