NCT04009850 is a NA clinical trial of Cigarette Brand Switching in Tobacco Use, sponsored by Yale University.

Who is sponsoring NCT04009850?

NCT04009850 is sponsored by Yale University.

What drugs are being tested in NCT04009850?

Interventions in NCT04009850: Cigarette Brand Switching, E-cigarette Flavor.

What condition does NCT04009850 study?

NCT04009850 studies Tobacco Use.

Is NCT04009850 still recruiting?

NCT04009850 is currently terminated. Last updated 8 March 2024.

Are results published for NCT04009850?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2024-03-08 · How we verify

NCT04009850

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior

Terminated NA Results posted Last updated 8 March 2024

What this trial tests

NA trial testing Cigarette Brand Switching in Tobacco Use in 3 participants. Terminated before completion.

Timeline

1 July 2019

Primary endpoint
9 November 2019

31 January 2022

Quick facts

Lead sponsor	Yale University
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	3
Start date	1 July 2019
Primary completion	9 November 2019
Estimated completion	31 January 2022
Sites	1 location across United States

Drugs / interventions tested

Cigarette Brand Switching
E-cigarette Flavor

Conditions studied

Tobacco Use — all drugs for Tobacco Use →

Sponsor

Yale University

Who can join

18 and older, any sex, with Tobacco Use. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Total Number of Cigarettes Smoked Primary · Week 6

Self-reported total number of cigarettes smoked per day (Timeline Follow Back)

Group	Value	95% CI
Menthol E-cigarette	19	± 16

Tobacco Product Satisfaction Secondary · Week 6

Self-reported subjective ratings of satisfaction with tobacco products (Modified Cigarette/E-cigarette Evaluation Questionnaire), rated 1-7 with higher scores indicating greater satisfaction

Group	Value	95% CI
Menthol E-cigarette	1.7	± 1.6

Motivation to Quit Smoking Secondary · Week 6

Self-reported motivation to quit smoking cigarettes (Contemplation Ladder), rated 1-10, higher scores indicate greater motivation to quit

Group	Value	95% CI
Menthol E-cigarette	7.7	± 2.1

Nicotine Dependence Secondary · Week 6

Self-reported nicotine dependence (NIH Promis Dependence Measure), rated 1-5, higher scores indicate greater dependence

Group	Value	95% CI
Menthol E-cigarette	3.8	± 1.1

Sponsor's own description

This study will investigate within-person changes in smoking behavior when current menthol smokers are switched to non-menthol cigarettes and either tobacco or menthol flavored e-cigarettes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Cigarette Brand Switching

Trials testing the same drug.

NCT03075839 — Impact of Switching to Non-Menthol Cigarettes Among Smokers · NA · completed

Other recruiting trials for Tobacco Use

Currently open trials in the same condition.

NCT07162935 — Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY) · NA · recruiting
NCT07132814 — Abuse Liability for Five Modern Oral Nicotine Products · NA · recruiting
NCT07148232 — Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness · Phase 4 · recruiting
NCT06983678 — Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chron · NA · recruiting
NCT06922617 — STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking · NA · recruiting

Other Yale University trials

Trials by the same sponsor.

NCT06900998 — Pilot Study: Effects of Nimodipine on Alcohol Drinking · Phase 2 · not yet recruiting
NCT04910984 — Developing a Chatbot to Promote HIV Testing · NA · not yet recruiting
NCT07458087 — Accuracy of the Accuro 3S · NA · not yet recruiting
NCT07398404 — A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Pa · Phase 1, PHASE2 · not yet recruiting
NCT07305324 — Improving Liver Fibrosis Diagnosis in Primary Care Using FibroX AI · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04009850 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yale University
Last refreshed: 8 March 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04009850.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing