NCT04008589 is a Phase 1, PHASE2 clinical trial of repetitive transorbital AC Stimulation in Stroke, sponsored by University of Magdeburg.

Who is sponsoring NCT04008589?

NCT04008589 is sponsored by University of Magdeburg.

What drugs are being tested in NCT04008589?

Interventions in NCT04008589: repetitive transorbital AC Stimulation, combination of transcranial direct current stimulaton and rtACS.

What condition does NCT04008589 study?

NCT04008589 studies Stroke, Electrical Stimulation.

Is NCT04008589 still recruiting?

NCT04008589 is currently completed. Last updated 10 November 2020.

Last reviewed 2020-11-10 · How we verify

NCT04008589

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Non-invasive Current Stimulation for Restoration of Vision

Completed Phase 1, PHASE2 Last updated 10 November 2020

What this trial tests

Phase 1, PHASE2 trial testing repetitive transorbital AC Stimulation in Stroke in 45 participants. Completed in 5 November 2020.

Timeline

1 January 2014

Primary endpoint
31 March 2016

5 November 2020

Quick facts

Lead sponsor	University of Magdeburg
Phase	Phase 1, PHASE2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	45
Start date	1 January 2014
Primary completion	31 March 2016
Estimated completion	5 November 2020
Sites	1 location across Germany

Drugs / interventions tested

repetitive transorbital AC Stimulation
combination of transcranial direct current stimulaton and rtACS

Conditions studied

Stroke — all drugs for Stroke →
Electrical Stimulation — all drugs for Electrical Stimulation →

Sponsor

University of Magdeburg

Who can join

Adults 18 to 75, any sex, with Stroke or Electrical Stimulation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to evaluate effects of current stimulation of the brain on vision parameters, vision-related quality of life, and physiological parameters to uncover mechanisms of vision restoration. These include EEG-spectra and coherence measures, and visual evoked potentials. The design of stimulation protocols involves an appropriate sham-stimulation condition and sufficient follow-up periods to test whether the effects are stable. This is the first application of non-invasive current stimulation for vision rehabilitation in stroke-related visual field deficits.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of Electrical Stimulation on Ocular Cells: A Means for Improving Ocular Tissue Engineering and Treatments of Eye Diseases.
Sanie-Jahromi F, Azizi A, Shariat S, Johari M. · · 2021 · cited 9× · PMID 34840978 · DOI 10.1155/2021/6548554

Verify or expand the search:

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
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NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other University of Magdeburg trials

Trials by the same sponsor.

NCT04010994 — Treatment of Patients With Optic Nerve Damage Patients Using Electrostimulation · Phase 1, PHASE2 · unknown
NCT04037384 — Training of Eye Movements in Glaucoma · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04008589 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Magdeburg
Last refreshed: 10 November 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04008589.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing