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NCT04008446: Vit B12
Effect of Vitamin B12 on the Development of Sepsis, in Culture Positive Patients
trial in Bacteremia in 100 participants. Completed in 31 December 2022.
11 November 2022
Quick facts
| Lead sponsor | University of Zurich |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 June 2019 |
| Primary completion | 11 November 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across Switzerland |
Conditions studied
- Bacteremia — all drugs for Bacteremia →
Sponsor
University of Zurich
Who can join
18 and older, any sex, with Bacteremia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an prospective observational study assessing the effect of vitamin B12 on the odds of developing sepsis in patients with infection confirmed by a positive culture result. The hypothesis is that patients with infection confirmed by positive cultures who develop sepsis have lower vitamin B12 levels than patients infection, confirmed by positive cultures, who do not develop sepsis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vitamin B12 status and the risk of developing sepsis in patients with bacterial infection: a prospective observational cohort study.
Pregernig A, Held U, Schläpfer M, Beck-Schimmer B. · · 2024 · cited 3× · PMID 39134986 · DOI 10.1186/s12916-024-03552-3
Verify or expand the search:
- PubMed search for NCT04008446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Zurich trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04008446 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Zurich
- Last refreshed: 10 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04008446.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing