NCT03999502 is a NA clinical trial of Endomina in GERD, sponsored by Erasme University Hospital.

Who is sponsoring NCT03999502?

NCT03999502 is sponsored by Erasme University Hospital.

What drugs are being tested in NCT03999502?

Interventions in NCT03999502: Endomina.

Is NCT03999502 still recruiting?

NCT03999502 is currently status unknown. Last updated 2 March 2021.

Last reviewed 2021-03-02 · How we verify

NCT03999502

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Endomina Suturing Device as a Treatment of GERD.

Status unknown NA Last updated 2 March 2021

What this trial tests

NA trial testing Endomina in GERD in 15 participants. Status unknown.

Timeline

15 May 2018

Primary endpoint
12 May 2021

12 May 2022

Quick facts

Lead sponsor	Erasme University Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	15
Start date	15 May 2018
Primary completion	12 May 2021
Estimated completion	12 May 2022
Sites	1 location across Belgium

Drugs / interventions tested

Endomina

Conditions studied

GERD — all drugs for GERD →

Sponsor

Erasme University Hospital

Who can join

Adults 21 to 70, any sex, with GERD. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Gastroesophageal Reflux Disease (GERD) is a common problem affecting 10-20% of the population in the Western World. Surgical therapy is able to restore the EGJ barrier function against reflux of the gastric content, decreases symptoms and improves the quality of life in GERD patients. However, there remain concerns regarding postoperative adverse events and the durability of the surgical procedure. The ability to perform endoscopic full-thickness plications with Endomina-v2 will be used to assess safety and feasibility of the procedure in reducing GERD in patients suffering with chronic GERD, unsatisfied with PPIs, and/or complaining of persistent GERD symptoms despite PPI use.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pilot study of an endoluminal-suturing device as a treatment for patients with gastroesophageal reflux disease.
Louis H, Van Ouytsel P, Leclercq L, Houinsou Hans M, et al · · 2023 · PMID 38026783 · DOI 10.1055/a-2185-5947

Verify or expand the search:

Other trials of Endomina

Trials testing the same drug.

NCT03843801 — A Prospective Study to Evaluate the Suture Pattern With the Endomina Suturing Device for Endoscopic Sutured Gastroplasty · NA · completed
NCT03608540 — Endomina as an Aid for Endoscopic Full Thickness Resection · NA · terminated
NCT03609073 — Endomina Diverticulum · NA · terminated
NCT03608267 — Safety and Feasibility of Endomina, an Candy Cane Syndrome Endoluminal Suturing Device · NA · completed
NCT03675035 — Endomina Post RYGB · NA · completed

Other recruiting trials for GERD

Currently open trials in the same condition.

NCT06953986 — A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA · NA · recruiting
NCT07421011 — Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 · Phase 1 · recruiting
NCT07268820 — Heartburn, Gastroesophageal Reflux Disease · Phase 4 · recruiting
NCT06955520 — Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM · NA · recruiting
NCT06641375 — Anti-Reflux Endoscopic Therapy Using Argon Plasma Coagulation (AREA) in Gastroesophageal Reflux Disease (GERD) Patients: · NA · recruiting

Other Erasme University Hospital trials

Trials by the same sponsor.

NCT07532733 — Respiratory and Haemodynamic Effects of Conscious Sedation With Dexmedetomidine for a TAVI Procedure · NA · not yet recruiting
NCT07532681 — Effect of Early Versus Late Surgical Intercostal Block on Postoperative Pain Relief Following Video-Assisted Thoracic Su · NA · not yet recruiting
NCT07457879 — Impact of the Reimbursement of Fibrinogen in Cardiac Surgery · not yet recruiting
NCT07184593 — Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill Patients · not yet recruiting
NCT07369232 — Cerebral Hemodynamic Effects of Oxygen and Antioxidants (CHEOXANT) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03999502 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Erasme University Hospital
Last refreshed: 2 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03999502.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing