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NCT03998917: PIONNIER
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
trial testing Discrimination of neuromuscular alterations protocol in Chronic Kidney Failure. Withdrawn.
1 September 2020
Quick facts
| Lead sponsor | Centre Hospitalier le Mans |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 1 September 2019 |
| Primary completion | 1 September 2020 |
| Estimated completion | 31 December 2020 |
Drugs / interventions tested
- Discrimination of neuromuscular alterations protocol
Conditions studied
- Chronic Kidney Failure — all drugs for Chronic Kidney Failure →
- Chronic Kidney Disease stage3 — all drugs for Chronic Kidney Disease stage3 →
- Chronic Kidney Disease, Stage 4 (Severe) — all drugs for Chronic Kidney Disease, Stage 4 (Severe) →
- Chronic Kidney Disease Stage 5 — all drugs for Chronic Kidney Disease Stage 5 →
Sponsor
Centre Hospitalier le Mans
Who can join
18 and older, any sex, with Chronic Kidney Failure or Chronic Kidney Disease stage3. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The evolution of chronic kidney disease (CKD) causes a systemic upheaval on the body and a deep fatigue is very often described by patients (50-70% of the patients) even before the start of dialysis (pre-dialysis). This fatigue has many origins, and one of them probably stems from a deterioration of neuromuscular abilities. Very few studies have examined the physiological aspects of neuromuscular fatigue in pre-dialysis patients, and shedding light on potential deficits at this level would allow safe and efficient implementation of adapted physical activity programs. Our study aims to characterize the pathophysiology of neuromuscular capabilities in chronic advanced renal failure in pre-dialysis patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03998917
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other recruiting trials for Chronic Kidney Failure
Currently open trials in the same condition.
- NCT07348237 — A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006) · Phase 1 · recruiting
- NCT06981585 — Physical Impairments in Children With Chronic Renal Failure · recruiting
- NCT06660160 — Group Exercise Program Supported By Audiovisual Media During Hemodialysis · NA · active not recruiting
- NCT05562869 — Belatacept as a Replacement for CNIs 3 to 12 Months Post-transplantation in Patients With Early Graft Dysfunction · Phase 3 · recruiting
- NCT05445219 — Identifying Therapeutic Hemodialysis Targets Through Cerebrovascular Reactivity; RESPIRACT 2 · active not recruiting
Other Centre Hospitalier le Mans trials
Trials by the same sponsor.
- NCT07365644 — Prophylactic ANTicoagulation With HEparine in Critically Ill Patients With Renal Impairment · not yet recruiting
- NCT07301957 — Impact of Early Rupture of the Residual Membrane on Latency Before Labour Begins · NA · not yet recruiting
- NCT07458477 — Digital Audiometer vs. Conventional Audiometer (Gold Standard): Study of Tonal and Vocal Recognition Thresholds · NA · recruiting
- NCT06799806 — The Impact of the Therapeutic Virtual Reality Headset on Patient Anxiety in the Waiting Room Before Flexible Bronchoscop · NA · recruiting
- NCT05915663 — Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03998917 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier le Mans
- Last refreshed: 25 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03998917.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing