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NCT03998501
fMRI to Examine the Effect of CBTm to Increase Resiliency for PTSD
NA trial testing Cognitive Behavioral Therapy with Mindfulness Class in Stress Disorders, Post-Traumatic in 40 participants. Participants enrolled and being followed up; not accepting new ones.
31 March 2021
Quick facts
| Lead sponsor | University of Manitoba |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 40 |
| Start date | 1 September 2019 |
| Primary completion | 31 March 2021 |
| Estimated completion | 31 March 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Cognitive Behavioral Therapy with Mindfulness Class
Conditions studied
- Stress Disorders, Post-Traumatic — all drugs for Stress Disorders, Post-Traumatic →
Sponsor
University of Manitoba
Who can join
18 and older, any sex, with Stress Disorders, Post-Traumatic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A substantial proportion of public safety personnel (PSP) develop service-related posttraumatic stress disorder (PTSD). PTSD is associated with a range of negative outcomes and its exact underlying neurophysiological mechanism is still not well understood. Cognitive behavioral therapy (CBT) is commonly prescribed to treat PTSD, and recent studies suggest that it may be effective in preventing the condition. We have developed a 5-session class focused on teaching introductory CBT skills to prevent and manage psychological distress, and we are currently in the process of launching a clinical trial to demonstrate its effectiveness in preventing PTSD and related conditions in PSP. In the proposed adjunctive study to this trial, we will quantitate the brain connectivity signature that is specific to the PTSD-resilience, and examine whether the classes increase this resilience-related brain mechanism.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03998501
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
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Other University of Manitoba trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03998501 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Manitoba
- Last refreshed: 3 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03998501.
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