NCT03997669 is a clinical trial of Collection of pleural effusion in Pleural Diseases, sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology.

What drugs are being tested in NCT03997669?

Interventions in NCT03997669: Collection of pleural effusion.

What condition does NCT03997669 study?

NCT03997669 studies Pleural Diseases.

Is NCT03997669 still recruiting?

NCT03997669 is currently completed. Last updated 16 November 2021.

Last reviewed 2021-11-16 · How we verify

NCT03997669

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Diagnosis and Mechanism of Pleural Effusion

Completed Last updated 16 November 2021

What this trial tests

trial testing Collection of pleural effusion in Pleural Diseases in 2,000 participants. Completed in 1 October 2021.

Timeline

1 July 2019

Primary endpoint
1 February 2020

1 October 2021

Quick facts

Lead sponsor	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Status	Completed
Study type	OBSERVATIONAL
Enrollment	2,000
Start date	1 July 2019
Primary completion	1 February 2020
Estimated completion	1 October 2021
Sites	1 location across China

Drugs / interventions tested

Collection of pleural effusion

Conditions studied

Pleural Diseases — all drugs for Pleural Diseases →

Sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Who can join

Adults 18 to 80, any sex, with Pleural Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The diagnosis, treatment and mechanism of pleural diseases

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Metabolic characteristics of large and small extracellular vesicles from pleural effusion reveal biomarker candidates for the diagnosis of tuberculosis and malignancy.
Luo P, Mao K, Xu J, Wu F, et al · · 2020 · cited 50× · PMID 32944177 · DOI 10.1080/20013078.2020.1790158
Development and validation of a novel scoring system developed from a nomogram to identify malignant pleural effusion.
Wang S, Tian S, Li Y, Zhan N, et al · · 2020 · cited 42× · PMID 32739872 · DOI 10.1016/j.ebiom.2020.102924
Driverless artificial intelligence framework for the identification of malignant pleural effusion.
Li Y, Tian S, Huang Y, Dong W. · · 2021 · cited 14× · PMID 33045678 · DOI 10.1016/j.tranon.2020.100896

Verify or expand the search:

Other recruiting trials for Pleural Diseases

Currently open trials in the same condition.

NCT06790082 — The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma · Phase 2 · recruiting
NCT06964308 — Thoracoscopic Pleural Biopsy in Sohag University Hospital · NA · recruiting
NCT06180603 — Strategy for Prompt and Effective Thoracentesis in the Emergency Department · NA · recruiting
NCT06226909 — The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease · NA · recruiting

Other Union Hospital, Tongji Medical College, Huazhong University of Science and Technology trials

Trials by the same sponsor.

NCT07521124 — ABC Maintenance Therapy for AML · NA · not yet recruiting
NCT07497243 — X-ray Assisted Diagnostic System · not yet recruiting
NCT07520123 — Union-FAST: An Intelligent-Agent Intervention to Increase Antiviral Treatment Uptake in Diagnosed-but-Untreated Hepatiti · NA · not yet recruiting
NCT06970262 — FMT for Lung and Associated-organ Rescue Efficacy in ARDS Patients · NA · recruiting
NCT07509424 — Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Lo · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03997669 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Last refreshed: 16 November 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03997669.

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