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NCT03996915: Halitosis
Evaluation of Halitosis After Treatment With Photodynamic Therapy Associated With Periodontal Treatment
NA trial testing Pdt Photodynamic Therapy in Halitosis in 40 participants. Completed in 1 December 2019.
1 November 2019
Quick facts
| Lead sponsor | University of Nove de Julho |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 January 2019 |
| Primary completion | 1 November 2019 |
| Estimated completion | 1 December 2019 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Pdt Photodynamic Therapy
- tongue scrapper
Conditions studied
- Halitosis — all drugs for Halitosis →
Sponsor
University of Nove de Julho
Who can join
Adults 18 to 60, any sex, with Halitosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this randomized, controlled clinical trial was to treat oral halitosis in healthy adults with photodynamic therapy associated with periodontal treatment and follow them up for 3 months. The participants with halitosis will be randomized into two groups: G1-treatment with photodynamic therapy or G2-cleaning of the tongue with a tongue scraper . Halitosis were evaluated measuring volatile sulfur compounds using gas chromatography After the treatments, a second evaluation will be performed, along with a microbiological analysis (qPCR) for the identification of the bacteria T. denticola
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Evaluation of halitosis in adult patients after treatment with photodynamic therapy associated with periodontal treatment: Protocol for a randomized, controlled, single-blinded trial with 3-month follow up.
Romero SDS, Schalch TO, do Vale KL, Ando ES, et al · · 2019 · cited 3× · PMID 31574796 · DOI 10.1097/md.0000000000016976
Verify or expand the search:
- PubMed search for NCT03996915
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Halitosis
Currently open trials in the same condition.
- NCT07463859 — Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabet · NA · recruiting
- NCT06900881 — Role of Kefir Mouth Wash in Oral Health Status Amelioration · Phase 2, PHASE3 · recruiting
- NCT06882564 — Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis. · Phase 3 · recruiting
- NCT06583720 — Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of Halitosis · Phase 1 · recruiting
- NCT06483646 — Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis · NA · recruiting
Other University of Nove de Julho trials
Trials by the same sponsor.
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- NCT06984796 — Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD) · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03996915 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Nove de Julho
- Last refreshed: 29 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03996915.
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