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NCT03995342
The Correlation and Intervention of Intestinal Flora and Frailty in the Elderly
NA trial testing Inulin in Frailty Syndrome in 300 participants. Enrolling by invitation.
31 December 2024
Quick facts
| Lead sponsor | Xijing Hospital |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 300 |
| Start date | 1 August 2019 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Inulin — full drug profile →
- Maltodextrin (MALTODEXTRIN) — full drug profile →
Conditions studied
- Frailty Syndrome — all drugs for Frailty Syndrome →
Sponsor
Xijing Hospital
Who can join
65 and older, any sex, with Frailty Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aim to evaluate the improvement and correlation of soluble dietary fiber (prebiotics) in the frailty of elderly people by a randomized, double-blind, placebo-controlled clinical trial.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Looking at frailty and intrinsic capacity through a geroscience lens: the ICFSR & Geroscience Task Force.
de Souto Barreto P, Rolland Y, Ferrucci L, Arai H, et al · · 2023 · cited 21× · PMID 37985720 · DOI 10.1038/s43587-023-00531-w -
Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled trial.
Yang J, Hou L, Wang A, Shang L, et al · · 2024 · cited 17× · PMID 39286985 · DOI 10.1172/jci176507
Verify or expand the search:
- PubMed search for NCT03995342
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Inulin
Trials testing the same drug.
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- NCT07525180 — Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort · NA · not yet recruiting
- NCT06372249 — A Clinical Trial of Soluble Fiber for Asthma · Phase 2 · recruiting
- NCT06866262 — Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell · Phase 1, PHASE2 · recruiting
- NCT06607523 — The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms · NA · recruiting
Other recruiting trials for Frailty Syndrome
Currently open trials in the same condition.
- NCT07465159 — Multimodal Prehabilitation of Frail Patients Undergoing Elective Knee or Hip Replacement · NA · recruiting
- NCT07258615 — Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Trainin · NA · active not recruiting
- NCT07348081 — Real World Evidence to Assess the Value of a Digital Care Coordination and Monitoring Program for Supporting Caregivers · NA · recruiting
- NCT07338929 — Physical Performance Assessment in Kidney Transplant Evaluation · recruiting
- NCT07071142 — Frailty and Outcomes in Older Heart Failure Patients With Ejection Fraction >40% · active not recruiting
Other Xijing Hospital trials
Trials by the same sponsor.
- NCT07532096 — Extended Sentinel Lymph Node Biopsy With Methylene Blue Single Tracer Post-Neoadjuvant Therapy for Node-Positive Breast · NA · not yet recruiting
- NCT07519018 — TIS for Drug Resistant TLE · NA · not yet recruiting
- NCT07518992 — Correlation Between Preoperative Sleep and Postoperative Brain and Renal Dysfunction · not yet recruiting
- NCT07466303 — Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer · Phase 2 · not yet recruiting
- NCT07474142 — A Multicenter, Prospective Study on the Prognostic Value of PSMA PET in Patients With Newly Diagnosed, Treatment-naïve P · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03995342 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xijing Hospital
- Last refreshed: 17 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03995342.
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