Adults 6 to 8, any sex, with Reading Learning Disability or Math Learning Disability. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Word Reading Fluency-2 (Zumeta et al., 2012)Primary· an average of 25 weeks
Students have 1 min to read 60 words randomly sampled/presented in bands of 5 words from most frequent words; then from next-most frequent words; etc. Student's score is the number of words read correctly. Two forms are given, and student's final score is the average score on the two forms.
Group
Value
95% CI
Coordinated Reading and Math Intervention
10.216
± 8.916
Math Intervention
7.068
± 7.799
Reading Intervention
12.349
± 10.158
Business-as-usual Control
7.385
± 8.178
Sight Word Efficiency (TOWRE2; Wagner et al., 2012)Primary· an average of 25 weeks
Students have 45 seconds to read a list of words beginning with very simple words followed by words of increasing difficulty. Student's score is the number of words read correctly.
Group
Value
95% CI
Coordinated Reading and Math Intervention
17.567
± 11.289
Math Intervention
14.405
± 10.403
Reading Intervention
19.630
± 11.402
Business-as-usual Control
14.718
± 10.588
Woodcock-Johnson IV - Letter Word Identification (Woodcock-Johnson 2014).Primary· an average of 25 weeks
Students read aloud letters followed by simple words followed by words of increasing difficulty. Test ends when after six incorrect responses. Student's score is the number of correct responses.
Group
Value
95% CI
Coordinated Reading and Math Intervention
24.284
± 8.026
Math Intervention
21.459
± 9.036
Reading Intervention
26.616
± 8.015
Business-as-usual Control
21.756
± 7.294
Arithmetic Combinations Fluency (Fuchs et al., 2003)Primary· an average of 25 weeks
Students have 1 minute to write answers for 25 addition items; same for 25 subtraction items (sums \& minuends 5-12). Student's score is number correct across all 50 items.
Group
Value
95% CI
Coordinated Reading and Math Intervention
11.269
± 8.233
Math Intervention
15.014
± 10.550
Reading Intervention
6.849
± 6.628
Business-as-usual Control
6.269
± 5.986
Double-Digit Calculations Fluency (Fuchs et al., 2003)Primary· an average of 25 weeks
Students have 10 min to write answers to 20 addition problems with 2-digit addends without regrouping and 20 subtraction problems with double-digit minuends and subtrahends without regrouping. The score is number correct across all 40 items.
Group
Value
95% CI
Coordinated Reading and Math Intervention
6.284
± 6.433
Math Intervention
8.649
± 7.925
Reading Intervention
0.740
± 2.517
Business-as-usual Control
1.038
± 3.077
Woodcock-Johnson IV - Calculations (Woodcock-Johnson 2014)Primary· an average of 25 weeks
Students solve mathematical computation problems beginning with simple basic facts followed by problems of increasing difficulty. Test ends when the student misses 6 consecutive problems. Student's score is the number of correct responses.
Group
Value
95% CI
Coordinated Reading and Math Intervention
13.090
± 4.754
Math Intervention
13.811
± 4.550
Reading Intervention
10.795
± 4.595
Business-as-usual Control
9.679
± 4.697
Sponsor's own description
The main purpose of this clinical trials is to explore short-term effects of coordinated intervention versus the business-as-usual school program on the primary endpoints of post-intervention word-reading fluency and arithmetic fluency. The study population is students who begin 1st grade with delays in word reading and calculations. Students who meet entry criteria are randomly assigned to coordinated intervention across reading and math, reading intervention, math intervention, and a business-as-usual control group (schools' typical program). The 3 researcher-delivered interventions last 15 weeks (3 sessions per week; 30 minutes per session). Students in all 4 conditions are tested before researcher-delivered intervention begins and after it ends.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University
Last refreshed: 23 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03991234.