NCT03990389

Tracking Depression Symptoms With a Health Chatbot

Completed NA Results posted Last updated 12 May 2022

What this trial tests

NA trial testing Chatbot Intervention in Depression, Postpartum in 31 participants. Completed in 29 February 2020.

Timeline

20 February 2019

Primary endpoint
29 February 2020

29 February 2020

Quick facts

Lead sponsor	University of Chicago
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	31
Start date	20 February 2019
Primary completion	29 February 2020
Estimated completion	29 February 2020
Sites	2 locations across United States

Drugs / interventions tested

• Chatbot Intervention

Conditions studied

• Depression, Postpartum — all drugs for Depression, Postpartum →
• Depression, Unipolar — all drugs for Depression, Unipolar →

Sponsor

University of Chicago

Who can join

18 and older, any sex, with Depression, Postpartum or Depression, Unipolar. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Longitudinal Change in Depression Severity Primary · 3 months

Measured by the Edinburgh Postnatal Depression Scale (EPDS) Range 0-30 (dimensionless) Risk of depression goes up with an increasing score

baseline

Group	Value	95% CI
No Intervention: Usual Care Group	16.13	± 1.17
Experimental: Chabot Care Group	14.06	± 1.13

month 1

Group	Value	95% CI
No Intervention: Usual Care Group	10.47	± 1.29
Experimental: Chabot Care Group	10.69	± 1.13

month 2

Group	Value	95% CI
No Intervention: Usual Care Group	8.23	± 1.33
Experimental: Chabot Care Group	11.35	± 1.19

month 3

Group	Value	95% CI
No Intervention: Usual Care Group	9.64	± 1.33
Experimental: Chabot Care Group	10.87	± 1.16

Change in Depression Severity Secondary · 3 months

Measured by the Computerized Adaptive Test-Depression Inventory (CAT-DI) and calculated change in Edinburgh Postnatal Depression Scale (EPDS) between Baseline and 3 months. Edinburgh Postnatal Depression Scale (EPDS) Range 0-30 (dimensionless) Risk of depression goes up with an increasing score

Group	Value	95% CI
No Intervention: Usual Care Group	-6.2	± 4.3
Experimental: Chabot Care Group	-3.1	± 5.4

Sponsor's own description

The goal of this research is to bridge a significant "effectiveness" gap in the treatment of depression. The investigators have developed a chatbot which will assist in performing measurement-based care (MBC) via Facebook Messenger. Participants will be randomized to either Usual Care or Usual Care with additional Chatbot Care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.