NCT03988829 (ViCTOR) is a NA clinical trial of Low-C in Cognitive Aging, sponsored by The University of Texas at Dallas.

Who is sponsoring NCT03988829?

NCT03988829 is sponsored by The University of Texas at Dallas.

What drugs are being tested in NCT03988829?

Interventions in NCT03988829: Low-C, High-C, High-C+.

What condition does NCT03988829 study?

NCT03988829 studies Cognitive Aging, Functional Magnetic Resonance Imaging.

Is NCT03988829 still recruiting?

NCT03988829 is currently completed. Last updated 28 January 2022.

Last reviewed 2022-01-28 · How we verify

NCT03988829: ViCTOR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Strategic Training to Optimize Neurocognitive Functions in Older Adults

Completed NA Last updated 28 January 2022

What this trial tests

NA trial testing Low-C in Cognitive Aging in 75 participants. Completed in 31 August 2021.

Timeline

30 September 2018

Primary endpoint
31 August 2021

31 August 2021

Quick facts

Lead sponsor	The University of Texas at Dallas
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	75
Start date	30 September 2018
Primary completion	31 August 2021
Estimated completion	31 August 2021
Sites	1 location across United States

Drugs / interventions tested

Low-C
High-C
High-C+

Conditions studied

Cognitive Aging — all drugs for Cognitive Aging →
Functional Magnetic Resonance Imaging — all drugs for Functional Magnetic Resonance Imaging →

Sponsor

The University of Texas at Dallas

Who can join

Adults 18 to 90, any sex, with Cognitive Aging or Functional Magnetic Resonance Imaging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of the present randomized control trial is to evaluate the efficacy of a novel cognitive training approach using simulated games, where older adults will learn to flexibly deploy attentional control during working memory, for prevention of Alzheimer's Disease (AD). Based on our extensive pilot work, we expect training-related enhancements in both neural and cognitive functions on a broad range of cognitive abilities due to the importance of attentional control and working memory in many types of cognition. These outcomes are widely applicable to the cognitive health and the quality of life of elderly Americans, and have further potential to offset degenerative processes common to normal aging.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Cognitive and structural predictors of novel task learning, and contextual predictors of time series of daily task performance during the learning period.
Smith ET, Skolasinska P, Qin S, Sun A, et al · · 2022 · cited 2× · PMID 36212037 · DOI 10.3389/fnagi.2022.936528

Verify or expand the search:

Other recruiting trials for Cognitive Aging

Currently open trials in the same condition.

NCT06726616 — Physical and Cognitive Aging Study in Older Adults · recruiting
NCT06721390 — Music Improvisation Training on Cognitive Function in Older Adults · NA · active not recruiting
NCT07165977 — Anti-inflammatory Probiotics in Cognitive Functioning · NA · active not recruiting
NCT06006962 — Aging Well Through Interactions and Scientific Education - Action Plan (AgeWISE-AP) · NA · recruiting
NCT05322343 — Biobank and Brain Health in Bordeaux. · recruiting

Other The University of Texas at Dallas trials

Trials by the same sponsor.

NCT07534397 — Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current · NA · not yet recruiting
NCT07354139 — Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter · NA · recruiting
NCT07206550 — The Role of Framing and Choice Architecture in Patients' Reactions and EHR Error Discovery and Reporting · NA · enrolling by invitation
NCT06731452 — Exploring Neurophysiological Markers of Brain Health · NA · recruiting
NCT06724887 — Brain Health on College Campuses · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03988829 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The University of Texas at Dallas
Last refreshed: 28 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03988829.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing