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Antimicrobial Therapy for Ulcerative Colitis (UC)
The Aim of this randoized controlled pilot study is to find a better treatment strategy for active UC based on the recent knowledge regarding the microbiota in UC and the beneficial or detrimental effects of antibiotics in restoring gut health and reducing inflammation. This study is designed to determine whether therapy with two antibiotics during a flare - amoxicillin and doxycillin, will be better than the current published antibiotic treatment combination using these antibiotics with metronidazole ( as the latter which may degrade beneficial species without adding benefit towards reducing pathobionts)
Details
| Lead sponsor | Wolfson Medical Center |
|---|---|
| Phase | PHASE2 |
| Status | TERMINATED |
| Enrolment | 20 |
| Start date | Thu Jul 25 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon May 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Ulcerative Colitis
Interventions
- amoxicillin, metronidazole and doxycycline
- amoxicillin and doxycyclin
Countries
Israel