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NCT03985735
Characterisation of Gut Microbiota, Bispectral Index Data and Plasma Kynurenine in Patients Undergoing Video-assisted Thoracic Surgery
trial testing General anesthesia in Lung Cancer in 20 participants. Completed in 20 January 2020.
31 December 2019
Quick facts
| Lead sponsor | China Medical University, China |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 August 2019 |
| Primary completion | 31 December 2019 |
| Estimated completion | 20 January 2020 |
| Sites | 1 location across China |
Drugs / interventions tested
- General anesthesia — full drug profile →
Conditions studied
- Lung Cancer — all drugs for Lung Cancer →
Sponsor
China Medical University, China
Who can join
Adults 18 to 75, any sex, with Lung Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is a case-controlled observational trial. Sixty patients will be divided into 2 groups (good or poor sleepers) depending on their first postoperative night Bispectral index data. Firstly, this study aims to characterise the gut and lung microbiota in patients with lung cancer treated with surgery. Secondly, it aims to evaluate microbiota and its influence on plasma kynurenine.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances.
Zhong H, Jiang M, Yuan K, Sheng F, et al · · 2025 · cited 1× · PMID 39924929 · DOI 10.1002/ame2.12557
Verify or expand the search:
- PubMed search for NCT03985735
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Lung Cancer
Currently open trials in the same condition.
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Other China Medical University, China trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03985735 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by China Medical University, China
- Last refreshed: 22 June 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03985735.
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