Who is sponsoring NCT03982615?

NCT03982615 is sponsored by University of Illinois at Chicago.

What drugs are being tested in NCT03982615?

Interventions in NCT03982615: Laser-Lok abutment, Standard healing abutment.

What condition does NCT03982615 study?

NCT03982615 studies Dental Implant Failure Nos.

Is NCT03982615 still recruiting?

NCT03982615 is currently status unknown. Last updated 26 March 2021.

Last reviewed 2021-03-26 · How we verify

NCT03982615: Laser-Lok

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Laser-modified Abutment Topography on Peri-implant Mucosal Integration

Status unknown NA Last updated 26 March 2021

What this trial tests

NA trial testing Laser-Lok abutment in Dental Implant Failure Nos in 20 participants. Status unknown.

Timeline

8 May 2019

Primary endpoint
30 July 2021

31 December 2021

Quick facts

Lead sponsor	University of Illinois at Chicago
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	8 May 2019
Primary completion	30 July 2021
Estimated completion	31 December 2021
Sites	1 location across United States

Drugs / interventions tested

Laser-Lok abutment
Standard healing abutment

Conditions studied

Dental Implant Failure Nos — all drugs for Dental Implant Failure Nos →

Sponsor

University of Illinois at Chicago

Who can join

18 and older, any sex, with Dental Implant Failure Nos. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a prospective randomized split mouth study intended to evaluate the healing and health of peri-implant mucosal tissue following placement of titanium abutments with or without laser-etching. Each subject will receive two implants. Following placement of the two 4.2mm diameter implants, one implant will receive (by randomization) a laser-etched abutment ('Laser-Lok'). The other implant will receive a standard, non-etched healing abutment. Subjects will be sequentially subdivided into four groups (n=5) and scheduled for a biopsy of the peri-implant tissues of both implants at either 8 weeks, 4 weeks, 2 weeks or 1 week after implant surgery. These biopsies, about the size of a grain of rice, will be analyzed using immunohistochemical and RNASeq techniques to identify molecular changes in response to laser etching. At approximately 8 weeks after implant surgery, subjects will have abutments removed from both implants and digital impressions taken for final crown fabrication. At approximately 11-12 weeks after implant surgery, final crowns will be placed. Subjects return to clinic at approximately 1 year post surgery for a final study visit to assess the peri-implant mucosa surrounding both implants as measured by bleeding upon probing, probing depth and peri-apical radiography.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Dental Implant Failure Nos

Currently open trials in the same condition.

NCT07348094 — Guided Lateral Sinus Lifting Using Autologous Serum Albumin/Platelet-Rich Fibrin · NA · recruiting
NCT05156294 — Effect of Soft Tissue Augmentation With an Acellular Dermal Matrix in Marginal Bone Levels Around Implants · Phase 3 · active not recruiting

Other University of Illinois at Chicago trials

Trials by the same sponsor.

NCT07498322 — Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System · NA · not yet recruiting
NCT07387705 — On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial · Phase 1 · not yet recruiting
NCT07504120 — The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis · NA · not yet recruiting
NCT07160582 — Cognitive-Motor Training for AD/ADRD Prevention · NA · not yet recruiting
NCT07498348 — Apple Watch Evaluation of Endodontics Occupational Stress · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03982615 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Chicago
Last refreshed: 26 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03982615.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing