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NCT03982147: STRATEGIC

White Matter Connections and Memory: the STRATEGIC Study

Status unknown Last updated 11 June 2019
What this trial tests

trial in Stroke in 193 participants. Status unknown.

Timeline
11 April 2014
Primary endpoint
7 June 2017
30 April 2022

Quick facts

Lead sponsorKing's College London
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment193
Start date11 April 2014
Primary completion7 June 2017
Estimated completion30 April 2022

Conditions studied

Sponsor

King's College London

Who can join

50 and older, any sex, with Stroke or Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In patients who have had a stroke, memory problems are common. Some patients with memory problems improve over the first year after stroke, but recovery is unpredictable. The STRATEGIC study assesses patients with recent stroke and follows them up after one year. The study uses cognitive testing and advanced MRI to understand the brain's mechanism for recovery from memory problems and to identify factors that may predict later recovery.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Cholinergic and hippocampal systems facilitate cross-domain cognitive recovery after stroke.
    O'Sullivan MJ, Oestreich LKL, Wright P, Clarkson AN. · · 2022 · cited 20× · PMID 35188545 · DOI 10.1093/brain/awac070
  2. Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: An <i>in vivo</i> PET Study With Neuropathological Comparison.
    Wright P, Veronese M, Mazibuko N, Turkheimer FE, et al · · 2020 · cited 14× · PMID 33178101 · DOI 10.3389/fneur.2020.541377
  3. Hyperconnectivity and altered interactions of a nucleus accumbens network in post-stroke depression.
    Oestreich LKL, Wright P, O'Sullivan MJ. · · 2022 · cited 13× · PMID 36415661 · DOI 10.1093/braincomms/fcac281
  4. Cardiovascular risk factors are associated with cognitive trajectory in the first year after stroke.
    Oestreich LK, Wright P, O'Sullivan MJ. · · 2024 · cited 4× · PMID 38988670 · DOI 10.1016/j.cccb.2024.100230
  5. Main Abstracts.
    · 2021 · cited 1× · PMID 35252582 · DOI 10.1177/23969873211034932

Verify or expand the search:

Other recruiting trials for Stroke

Currently open trials in the same condition.

Other King's College London trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03982147.

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