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NCT03980756
A Study to Compare PK, PD and Safety of the AD-206 and Esomeprazole
Phase 1 trial testing AD-206 20mg in Gastritis in 88 participants. Completed in 18 June 2020.
27 April 2020
Quick facts
| Lead sponsor | Addpharma Inc. |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 88 |
| Start date | 5 June 2019 |
| Primary completion | 27 April 2020 |
| Estimated completion | 18 June 2020 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- AD-206 20mg — full drug profile →
- Esomeprazole 20mg — full drug profile →
- AD-206 40mg — full drug profile →
- Esomeprazole 40mg — full drug profile →
Conditions studied
- Gastritis — all drugs for Gastritis →
Sponsor
Addpharma Inc. — full company profile →
Who can join
Adults 19 to 50, male only, with Gastritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A study to compare safety, pharmacokinetics and pharmacodynamics of AD-206 to Esomeprazole in healthy male volunteers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole.
Bae S, Kwon J, Lee SB, Jang IJ, et al · · 2021 · cited 8× · PMID 34992346 · DOI 10.2147/dddt.s341271
Verify or expand the search:
- PubMed search for NCT03980756
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Gastritis
Currently open trials in the same condition.
- NCT07032961 — A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening · recruiting
- NCT06948487 — Efficacy and Safety of FEXUCLUE Tab. In Patients With Acute or Chronic Gastritis · recruiting
- NCT06848400 — Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios · NA · recruiting
Other Addpharma Inc. trials
Trials by the same sponsor.
- NCT07444385 — A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 in Healthy Adult Male Subjects · Phase 1 · recruiting
- NCT07312799 — Evaluate the Pharmacokinetic Interaction and the Safety of AD-2321 and AD-2322 · Phase 1 · not yet recruiting
- NCT07385235 — Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151' · Phase 1 · recruiting
- NCT07312773 — A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-231A and AD-231B and AD-231C · Phase 1 · not yet recruiting
- NCT06884085 — A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03980756 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Addpharma Inc.
- Last refreshed: 13 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03980756.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing