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NCT03979157: MSOT_muscles
Non-invasive Molecular Imaging of Muscle Structure (MSOT_muscles)
NA trial testing Multispectral Optoacoustic Tomography in Muscular Diseases in 10 participants. Completed in 23 June 2020.
11 November 2019
Quick facts
| Lead sponsor | University of Erlangen-Nürnberg Medical School |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 10 |
| Start date | 14 October 2019 |
| Primary completion | 11 November 2019 |
| Estimated completion | 23 June 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Multispectral Optoacoustic Tomography
Conditions studied
- Muscular Diseases — all drugs for Muscular Diseases →
Sponsor
University of Erlangen-Nürnberg Medical School
Who can join
18 and older, any sex, with Muscular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to determine hemoglobin and collagen levels in muscles before and after exercise, and over time, using Multispectral Optoacoustic Tomography (MSOT). During MSOT, a transducer is placed on the skin similar to a conventional sonography and instead of sound, energy is supplied to the tissue by means of light flashes. This leads to a constant change of minimal expansions and contractions (thermoelastic expansion) of individual tissue constituents or molecules. The resulting sound waves can then be detected by the same examination unit.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Precision of handheld multispectral optoacoustic tomography for muscle imaging.
Wagner AL, Danko V, Federle A, Klett D, et al · · 2021 · cited 34× · PMID 33318928 · DOI 10.1016/j.pacs.2020.100220
Verify or expand the search:
- PubMed search for NCT03979157
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Multispectral Optoacoustic Tomography
Trials testing the same drug.
- NCT06994260 — Diagnostic Imaging of Vascular Malformations Using MSOT and ULM · not yet recruiting
- NCT06107179 — Monitoring of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography · unknown
- NCT06063785 — Multispectral Optoacoustic Tomography in Patients With Cystic Fibrosis · unknown
- NCT05083806 — MSOT in Pompe Disease · NA · completed
- NCT03490214 — Non-invasive Imaging of Muscle Structure in Duchenne Muscular Dystrophy Using Multispectral Optoacoustic Tomography · NA · completed
Other recruiting trials for Muscular Diseases
Currently open trials in the same condition.
- NCT05183152 — Non-invasive BCI-controlled Assistive Devices · NA · recruiting
Other University of Erlangen-Nürnberg Medical School trials
Trials by the same sponsor.
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- NCT07406191 — WB-EMS Effects on Cardiometabolic Risk Factors · NA · recruiting
- NCT07352540 — Single vs Triple Hyaluronic Acid in Knee Osteoarthritis · Phase 2, PHASE3 · not yet recruiting
- NCT07313878 — Evaluation of Acute and Chronic Nephrotoxicity in Acute Lymphatic Leukemia Patients Using Ultrasound Localization Micros · NA · recruiting
- NCT07121985 — Multispectral Optoacoustic Imaging for the Detection of Inflammation and Damage of Peripheral Nerves in Guillain-Barré S · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03979157 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Erlangen-Nürnberg Medical School
- Last refreshed: 7 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03979157.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing