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NCT03978702: IMMUNOPANC

Evaluation of the Impact of Pancreatectomy on Systemic Immunity

Status unknown NA Last updated 6 January 2022
What this trial tests

NA trial testing Blood sampling in Pancreas Cancer in 40 participants. Status unknown.

Timeline
24 February 2021
Primary endpoint
27 July 2022
27 July 2022

Quick facts

Lead sponsorInstitut Paoli-Calmettes
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment40
Start date24 February 2021
Primary completion27 July 2022
Estimated completion27 July 2022
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Institut Paoli-Calmettes — full company profile →

Who can join

18 and older, any sex, with Pancreas Cancer or Pancreatectomy; Hyperglycemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study aims at establishing the profile of the immune reaction that occurs in the early surgical suites after pancreatectomy. Blood samples will be collected before surgery, (Day-1), at day0, and after surgery at Day 1, Day 3, Day 7 at 1 year after pancreatectomy. Mass cytometry, genomic and transcriptomic approaches will be used to evaluate the immune systemic modulation after surgery.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Preoperative lymphocyte signature predicts pancreatic fistula after pancreatoduodenectomy.
    Garnier J, Bellan G, Palen A, Durand X, et al · · 2026 · PMID 41673079 · DOI 10.1038/s43856-026-01422-y
  2. Immediate variations in high-dimensional circulating immune cells following pancreatectomy.
    Garnier J, Palen A, Durand X, Ewald J, et al · · 2025 · PMID 41255738 · DOI 10.1002/cti2.70059
  3. Preoperative Lymphocyte Signature Predicts Pancreatic Fistula After Pancreatoduodenectomy
    Garnier J, Bellan G, Palen A, Durand X, et al · · 2025 · DOI 10.21203/rs.3.rs-5219663/v1

Verify or expand the search:

Other trials of Blood sampling

Trials testing the same drug.

Other recruiting trials for Pancreas Cancer

Currently open trials in the same condition.

Other Institut Paoli-Calmettes trials

Trials by the same sponsor.

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Data sources for this page

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