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NCT03977740
Chest PNF on Pulmonary Function in Parkinson Disease
NA trial testing chest PNF in Parkinson Disease in 20 participants. Status unknown.
10 June 2019
Quick facts
| Lead sponsor | Subhasish Chatterjee |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | sequential |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 January 2018 |
| Primary completion | 10 June 2019 |
| Estimated completion | 10 June 2019 |
| Sites | 1 location across India |
Drugs / interventions tested
- chest PNF
- Conventional
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
Subhasish Chatterjee
Who can join
Adults 50 to 70, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Parkinson disease (PD) is a progressive neurodegenerative disorder and characterized by tremor, rigidity and bradykinesia. Almost 84% of PD patient develops respiratory abnormalities and pointed as the most common cause of death. Airway obstruction, trunk muscle rigidity is the common cause of respiratory abnormalities. Purpose: The main purpose of the study will evaluate the efficacy of chest PNF on pulmonary function and chest wall mobility in PD. Methods: 20 participants will be recruited for study purpose and divide into two groups. Group= A will be the control group and participants will receive conventional treatment which includes deep breathing exercise and segmental breathing exercise, incentive spirometry etc for one week. Group= B participants will receive chest PNF exercise along with conventional treatment for a week. Pretreatment and post-treatment data will be recorded by the help of PFT (FVC, FEV1 \& FEV1/FVC) and chest wall expansion at axillary and xiphisternal level for data analysis. Data analysis will be done by paired t-test for within group and independent t-test will be used for the between-group variable. The level of significance will be set at 0.05.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Microtubule acetylation dyshomeostasis in Parkinson's disease.
Naren P, Samim KS, Tryphena KP, Vora LK, et al · · 2023 · cited 41× · PMID 37150812 · DOI 10.1186/s40035-023-00354-0
Verify or expand the search:
- PubMed search for NCT03977740
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03977740 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Subhasish Chatterjee
- Last refreshed: 6 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03977740.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing