Who is sponsoring NCT03972579?

NCT03972579 is sponsored by University of British Columbia.

What drugs are being tested in NCT03972579?

Interventions in NCT03972579: Graded exposure therapy, Pacing + mindfulness.

What condition does NCT03972579 study?

NCT03972579 studies Mild Traumatic Brain Injury.

Is NCT03972579 still recruiting?

NCT03972579 is currently completed. Last updated 16 November 2021.

Last reviewed 2021-11-16 · How we verify

NCT03972579

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Behavioral Profile Matching: A Precision Medicine Approach to Concussion Rehabilitation

Completed NA Last updated 16 November 2021

What this trial tests

NA trial testing Graded exposure therapy in Mild Traumatic Brain Injury in 64 participants. Completed in 1 July 2021.

Timeline

15 May 2019

Primary endpoint
15 February 2021

1 July 2021

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	64
Start date	15 May 2019
Primary completion	15 February 2021
Estimated completion	1 July 2021
Sites	1 location across Canada

Drugs / interventions tested

Graded exposure therapy
Pacing + mindfulness

Conditions studied

Mild Traumatic Brain Injury — all drugs for Mild Traumatic Brain Injury →

Sponsor

University of British Columbia

Who can join

Adults 18 to 69, any sex, with Mild Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

At least 1 in 5 people who sustain a concussion will have persistent symptoms and difficulties with daily activities. The researchers have identified two unhelpful coping styles following a concussion - avoidance and endurance. Individuals who engage in avoidance behavior may benefit from a different type of treatment than those who engage in endurance behavior. The researchers will evaluate whether assigning individuals to a specific psychologically-informed treatment tailored to their coping style is practical, acceptable, and beneficial for their recovery.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Psychological mediators of avoidance and endurance behavior after concussion.
Terpstra AR, Cairncross M, Yeates KO, Vranceanu AM, et al · · 2021 · cited 22× · PMID 34410757 · DOI 10.1037/rep0000390
Memory Perfectionism is Associated with Persistent Memory Complaints after Concussion.
Picon EL, Todorova EV, Palombo DJ, Perez DL, et al · · 2022 · cited 17× · PMID 35443277 · DOI 10.1093/arclin/acac021
Litigation, Performance Validity Testing, and Treatment Outcomes in Adults With Mild Traumatic Brain Injury.
Mikolic A, Panenka WJ, Iverson GL, Cotton E, et al · · 2024 · cited 4× · PMID 37773600 · DOI 10.1097/htr.0000000000000903

Verify or expand the search:

Other trials of Graded exposure therapy

Trials testing the same drug.

NCT03590236 — Graded Exposure Therapy in Chronic Pelvic Pain · NA · unknown

Other recruiting trials for Mild Traumatic Brain Injury

Currently open trials in the same condition.

NCT07246993 — Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms · NA · recruiting
NCT07356167 — Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury · NA · recruiting
NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
NCT06956417 — REhabilitation of MEMory Symptoms After BRain Concussion · NA · recruiting
NCT06217575 — Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans · NA · recruiting

Other University of British Columbia trials

Trials by the same sponsor.

NCT07340970 — Sensory Stimuli During Cesarean Delivery · not yet recruiting
NCT07481201 — Phenylalanine Requirements in the Menstrual Phases · NA · not yet recruiting
NCT07492095 — Leucine Requirements in School-Age Children · NA · not yet recruiting
NCT07429305 — Combined Tibial Nerve Stimulation and Standing for People With SCI · NA · recruiting
NCT07519928 — Exploring the Feasibility and Benefits of Implementing Pelvic Floor Muscle Training During Inpatient Rehabilitation for · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03972579 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
Last refreshed: 16 November 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03972579.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing