NCT03959319

Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders

Completed NA Last updated 31 January 2023

What this trial tests

NA trial testing Movement Pattern Training in Hip-related Groin Pain in 33 participants. Completed in 31 December 2022.

Timeline

1 July 2019

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	Washington University School of Medicine
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	33
Start date	1 July 2019
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across United States

Drugs / interventions tested

• Movement Pattern Training
• Manual Therapy

Conditions studied

• Hip-related Groin Pain — all drugs for Hip-related Groin Pain →
• Femoroacetabular Impingement — all drugs for Femoroacetabular Impingement →
• Dysplasia Mild — all drugs for Dysplasia Mild →
• Prearthritic Hip Disorder — all drugs for Prearthritic Hip Disorder →

Sponsor

Washington University School of Medicine

Who can join

Adults 18 to 40, any sex, with Hip-related Groin Pain or Femoroacetabular Impingement. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Significance: Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA). Our long term goal is to develop effective treatment strategies for people with PAHD that will improve function, decrease pain and prevent or delay the onset of OA. The purpose of this study is to compare movement pattern training (MoveTrain) and manual therapy (ManTher) in their effect on post-treatment, patient-reported outcomes and targeted impairments thought to contribute to PAHD.

This pilot study will collect sufficient data to power a future study that will determine the efficacy of MoveTrain compared to ManTher for people with PAHD. Participants with PAHD will be randomized into one of two treatment groups, MoveTrain or ManTher. The Hip disability and Osteoarthritis Outcome Score (HOOS) will be the primary outcome measure. A measure of hip adduction motion during functional tasks and quantitative sensory assessment (pain pressure threshold and temporal summation) will be the secondary measures used to assess the effect of respective treatment on the impairments thought to contribute to PAHD, thus addressing the mechanisms of pain. Upon completion of this study, we will be positioned to implement a large RCT (randomized clinical trial) to definitively assess the efficacy of MoveTrain and ManTher to improve PAHD.

Specific Aims: To obtain preliminary estimates of effect sizes for planning the future definitive randomized clinical trial,

Aim 1 (Function): we will compare post-treatment improvements in hip-specific, patient-reported outcomes among the two treatment groups. After treatment completion:

Aim 2 (Mechanism): we will compare pre- and post-treatment measures in lower extremity movement patterns during functional tasks (MoveTrain) and quantitative sensory testing (ManTher). After treatment completion:

Aim 3 (Prognosis): we will determine the association among personal factors at baseline (demographic and psychosocial) and treatment prognosis (improvement in HOOS).

Impact: Our line of research will improve our understanding of each proposed treatment and its effect on patient function and each treatment's targeted impairment. This improved understanding will lead to the development of treatment strategies that will ultimately result in comparative effectiveness studies of surgical and non-surgical treatment.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Comparison of Joint Mobilization and Movement Pattern Training for Patients With Hip-Related Groin Pain: A Pilot Randomized Clinical Trial.
   Harris-Hayes M, Zorn P, Steger-May K, Burgess MM, et al · · 2023 · cited 5× · PMID 37606253 · DOI 10.1093/ptj/pzad111
2. Personal factors and baseline function in patients undergoing non-operative management for chronic hip-related groin pain: a cross-sectional study.
   DeMargel RD, Steger-May K, Haroutounian S, Zorn P, et al · · 2023 · cited 1× · PMID 37937305 · DOI 10.1136/bmjsem-2023-001685