Who is sponsoring NCT03956719?

NCT03956719 is sponsored by Qilu Hospital of Shandong University.

What drugs are being tested in NCT03956719?

Interventions in NCT03956719: Autologous adipose-derived mesenchymal stem cells, abdominal liposuction.

What condition does NCT03956719 study?

NCT03956719 studies Knee Osteoarthritis.

Is NCT03956719 still recruiting?

NCT03956719 is currently status unknown. Last updated 16 September 2020.

Last reviewed 2020-09-16 · How we verify

NCT03956719

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells

Status unknown NA Last updated 16 September 2020

What this trial tests

NA trial testing Autologous adipose-derived mesenchymal stem cells in Knee Osteoarthritis in 8 participants. Status unknown.

Timeline

2 March 2019

Primary endpoint
9 September 2020

1 November 2020

Quick facts

Lead sponsor	Qilu Hospital of Shandong University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	8
Start date	2 March 2019
Primary completion	9 September 2020
Estimated completion	1 November 2020
Sites	1 location across China

Drugs / interventions tested

Autologous adipose-derived mesenchymal stem cells
abdominal liposuction

Conditions studied

Knee Osteoarthritis — all drugs for Knee Osteoarthritis →

Sponsor

Qilu Hospital of Shandong University

Who can join

Adults 15 to 65, any sex, with Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to explore the efficacy and safety of autologous adipose mesenchymal stem cells in the treatment of early knee arthritis. Investigator believes that autologous adipose mesenchymal stem cells can relieve pain, improve knee function, promote knee cartilage regeneration and improve life satisfaction of patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Stem cell injections for osteoarthritis of the knee.
Whittle SL, Johnston RV, McDonald S, Worthley D, et al · · 2025 · cited 11× · PMID 40169165 · DOI 10.1002/14651858.cd013342.pub2
Mesenchymal Stromal Cell-Based Therapy-An Alternative to Arthroplasty for the Treatment of Osteoarthritis? A State of the Art Review of Clinical Trials.
Maleitzke T, Elazaly H, Festbaum C, Eder C, et al · · 2020 · cited 8× · PMID 32630066 · DOI 10.3390/jcm9072062

Verify or expand the search:

Other trials of Autologous adipose-derived mesenchymal stem cells

Trials testing the same drug.

NCT04426643 — Treatment of Urinary Incontinence in Men After Prostatectomy With Autologous Adipose-derived Mesenchymal Stem Cells · Phase 1, PHASE2 · completed
NCT04446884 — Treatment of Stress Urinary Incontinence in Women With Autologous Adipose-derived Mesenchymal Stem Cells · Phase 1, PHASE2 · completed
NCT04457037 — Treatment of Patients With Trophic Ulcers Using Mesenchymal Stem Cells · Phase 1, PHASE2 · completed

Other recruiting trials for Knee Osteoarthritis

Currently open trials in the same condition.

NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting

Other Qilu Hospital of Shandong University trials

Trials by the same sponsor.

NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting
NCT07140419 — Coronary Computed Tomographic Angiography Combined With CT-FFR in Intermediate-Risk Chest Pain Patients. · NA · not yet recruiting
NCT07509879 — Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder · not yet recruiting
NCT07537374 — A Case-Control Observational Study of Peripheral Blood-Derived iPSC Models to Investigate Oligodendrocyte Lineage Develo · not yet recruiting
NCT07505940 — Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03956719 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Qilu Hospital of Shandong University
Last refreshed: 16 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03956719.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing