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NCT03955952
Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
trial testing Bariatric Surgery in Obesity in 13,722 participants. Completed in 26 August 2019.
12 July 2019
Quick facts
| Lead sponsor | The Cleveland Clinic |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 13,722 |
| Start date | 5 June 2019 |
| Primary completion | 12 July 2019 |
| Estimated completion | 26 August 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Bariatric Surgery
Conditions studied
- Obesity — all drugs for Obesity →
- Type2 Diabetes — all drugs for Type2 Diabetes →
- Bariatric Surgery Candidate — all drugs for Bariatric Surgery Candidate →
Sponsor
The Cleveland Clinic
Who can join
Adults 18 to 80, any sex, with Obesity or Type2 Diabetes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of the analysis was to evaluate the relationship between bariatric surgery and cardiovascular outcomes in obese patients with type 2 diabetes. This is a retrospective matched cohort study of patients with diabetes that underwent bariatric surgery at the Cleveland Clinic between 2004-2017. Each bariatric patient was matched to a non-surgical control with obesity and type 2 diabetes in a 1:5 ratio using data from the Electronic Medical Record (EMR). The maximum observation time was 10 years. Cumulative incidence rates for all-cause mortality and cardiovascular events were calculated at years 1, 3, 5, 7 and 10. Kaplan-Meier curves were created for all the outcomes with all-cause mortality considered as a completing risk.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity.
Aminian A, Zajichek A, Arterburn DE, Wolski KE, et al · · 2019 · cited 329× · PMID 31475297 · DOI 10.1001/jama.2019.14231
Verify or expand the search:
- PubMed search for NCT03955952
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other The Cleveland Clinic trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03955952 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Cleveland Clinic
- Last refreshed: 2 January 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03955952.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing