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NCT03948828
Clinical Study of NK Cells in the Treatment of Severe Endometriosis
Phase 1 trial testing Autologous NK cell therapy in NK Cell Mediated Immunity in 60 participants. Status unknown.
31 May 2022
Quick facts
| Lead sponsor | Shenzhen People's Hospital |
|---|---|
| Phase | Phase 1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 June 2019 |
| Primary completion | 31 May 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- Autologous NK cell therapy — full drug profile →
- GnRHa combained with reverse addition therapy — full drug profile →
Conditions studied
- NK Cell Mediated Immunity — all drugs for NK Cell Mediated Immunity →
- Endometriosis — all drugs for Endometriosis →
Sponsor
Shenzhen People's Hospital
Who can join
Adults 18 to 45, female only, with NK Cell Mediated Immunity or Endometriosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dysfunction of natural koller cells (NK cells) is an important factor in the development of endometriosis. NK cell therapy was applied to treat severe endometriosis, which is an exploration of the pathogenesis of this refractory disease.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Promises of Natural Killer Cell Therapy in Endometriosis.
Hoogstad-van Evert J, Paap R, Nap A, van der Molen R. · · 2022 · cited 25× · PMID 35628346 · DOI 10.3390/ijms23105539
Verify or expand the search:
- PubMed search for NCT03948828
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03948828 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shenzhen People's Hospital
- Last refreshed: 14 May 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03948828.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing