NCT03948438 is a clinical trial of Endoscopic septotomy in Zenker Diverticulum, sponsored by Istituto Clinico Humanitas.

Who is sponsoring NCT03948438?

NCT03948438 is sponsored by Istituto Clinico Humanitas.

What drugs are being tested in NCT03948438?

Interventions in NCT03948438: Endoscopic septotomy.

What condition does NCT03948438 study?

NCT03948438 studies Zenker Diverticulum.

Is NCT03948438 still recruiting?

NCT03948438 is currently recruiting now. Last updated 21 September 2022.

Last reviewed 2022-09-21 · How we verify

NCT03948438

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Endoscopic Treatment for Zenker's Diverticulum

Recruiting now Last updated 21 September 2022

What this trial tests

trial testing Endoscopic septotomy in Zenker Diverticulum in 400 participants. Currently enrolling.

Timeline

1 January 2009

Primary endpoint
30 December 2028

30 December 2028

Quick facts

Lead sponsor	Istituto Clinico Humanitas
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	400
Start date	1 January 2009
Primary completion	30 December 2028
Estimated completion	30 December 2028
Sites	1 location across Italy

Drugs / interventions tested

Endoscopic septotomy

Conditions studied

Zenker Diverticulum — all drugs for Zenker Diverticulum →

Sponsor

Istituto Clinico Humanitas

Who can join

18 and older, any sex, with Zenker Diverticulum. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Zenker's diverticulum (ZD) is a rare benign condition, due to an acquired sac-like outpouching of the mucosa and submucosa layers originating from the pharyngoesophageal junction. Endoscopic techniques like flexible endoscopic septum division (FESD) or per-oral endoscopic septotomy (POES), represent a minimally invasive alternative to surgery or to rigid endoscopic procedure to treat ZD. The goal of the research will be to evaluate the safety of the procedures and to measure Zenker-symptom severity in all patients treated by endoscopic procedures.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Cap-Assisted Endoscopic Septotomy of Zenker's Diverticulum: Early and Long-Term Outcomes.
Repici A, Cappello A, Spadaccini M, Nicoletti R, et al · · 2021 · cited 10× · PMID 34236338 · DOI 10.14309/ajg.0000000000001356
[Endoscopic treatment of Zenker's diverticulum].
Bourdial J, Lallemant Y. · · 1968 · cited 2× · PMID 4977436 · DOI 10.31525/ct1-nct03948438

Verify or expand the search:

Other recruiting trials for Zenker Diverticulum

Currently open trials in the same condition.

NCT04660214 — Minimally Invasive Endoscopic Treatment of Zenker's Diverticulum Comparing LigaSureTM vs SB-Knife. · NA · recruiting
NCT04117100 — Advanced Endo-therapeutic Procedure : Registry-based Observational Study · recruiting

Other Istituto Clinico Humanitas trials

Trials by the same sponsor.

NCT06944288 — Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination · NA · not yet recruiting
NCT07358247 — Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction · not yet recruiting
NCT07362342 — RIght VEntricle Response to Major Lung Resection in VATS and Robotic Surgery · not yet recruiting
NCT07346274 — Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy. · enrolling by invitation
NCT07491419 — The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03948438 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istituto Clinico Humanitas
Last refreshed: 21 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03948438.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing