NCT03945071 is a NA clinical trial of Punctal plug in Dry Eye Syndromes, sponsored by University of Oklahoma.

Who is sponsoring NCT03945071?

NCT03945071 is sponsored by University of Oklahoma.

What drugs are being tested in NCT03945071?

Interventions in NCT03945071: Punctal plug.

What condition does NCT03945071 study?

NCT03945071 studies Dry Eye Syndromes, Dry Eye, Ocular Surface Disease.

Is NCT03945071 still recruiting?

NCT03945071 is currently completed. Last updated 7 December 2023.

Last reviewed 2023-12-07 · How we verify

NCT03945071

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection

Completed NA Last updated 7 December 2023

What this trial tests

NA trial testing Punctal plug in Dry Eye Syndromes in 126 participants. Completed in 18 October 2020.

Timeline

1 June 2019

Primary endpoint
18 October 2020

18 October 2020

Quick facts

Lead sponsor	University of Oklahoma
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	prevention
Enrollment	126
Start date	1 June 2019
Primary completion	18 October 2020
Estimated completion	18 October 2020
Sites	1 location across United States

Drugs / interventions tested

Punctal plug

Conditions studied

Dry Eye Syndromes — all drugs for Dry Eye Syndromes →
Dry Eye — all drugs for Dry Eye →
Ocular Surface Disease — all drugs for Ocular Surface Disease →

Sponsor

University of Oklahoma

Who can join

18 and older, any sex, with Dry Eye Syndromes or Dry Eye. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to evaluate the effectiveness of punctal plugs in reducing ocular surface (eye surface) irritation after intravitreal injections prepared by povidone-iodine 5% solution.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The effect of punctal plugs in reducing ocular surface irritation after povidone-iodine preparation of intravitreal injection-a randomized trial.
Jin HD, Surbeck JW, Marsh HR, Ding K, et al · · 2022 · cited 6× · PMID 33746207 · DOI 10.1038/s41433-021-01476-3

Verify or expand the search:

Other trials of Punctal plug

Trials testing the same drug.

NCT03396809 — Punctal Plugs and Iodine Related Discomfort · NA · withdrawn

Other recruiting trials for Dry Eye Syndromes

Currently open trials in the same condition.

NCT07412860 — Clinical Investigation Between the Topical Administration of a Tear Substitute With Ancillary Medicinal Substance and Hy · NA · recruiting
NCT06913504 — Comparison Of Blue Light Filter Feature and Blue Blocking Lenses in Digital Device Users With Dry Eye Patients · NA · active not recruiting
NCT06913465 — The Impact of Hypothyroidism on Tear Production and Dry Eye Symptoms: Implications for Optometric Care · active not recruiting
NCT06831253 — Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome · NA · recruiting
NCT06220474 — Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD · NA · recruiting

Other University of Oklahoma trials

Trials by the same sponsor.

NCT07219706 — Dietary Fiber and Time Restricted Eating · NA · recruiting
NCT07494773 — Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection · Phase 1, PHASE2 · not yet recruiting
NCT07014605 — Smoking Cessation Program for Lao People With HIV · NA · not yet recruiting
NCT06960798 — Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno) · recruiting
NCT07491653 — Fiber mHealth Intervention for Prediabetes · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03945071 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Oklahoma
Last refreshed: 7 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03945071.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing