NCT03944538

Physical Activity Intervention for Improving Vascular Comorbidity Risk in Multiple Sclerosis

Terminated NA Last updated 30 May 2023

What this trial tests

NA trial testing Lifestyle Physical Activity in Multiple Sclerosis in 5 participants. Terminated before completion.

Timeline

21 July 2019

Primary endpoint
20 October 2020

20 October 2020

Quick facts

Lead sponsor	University of Ottawa
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	5
Start date	21 July 2019
Primary completion	20 October 2020
Estimated completion	20 October 2020
Sites	1 location across Canada

Drugs / interventions tested

• Lifestyle Physical Activity
• General Wellness

Conditions studied

• Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

University of Ottawa

Who can join

Adults 18 to 65, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vascular comorbidities, such as high cholesterol, obesity, high blood pressure, and diabetes, are common among people with multiple sclerosis (MS), and can negatively impact disease diagnosis, treatment, and progression. Physical inactivity may be one possible reason for this increased risk and may occur through changes in cardiorespiratory fitness (the ability of the body to transport and use oxygen during sustained physical activity). While exercise training is effective for improving fitness, factors such as accessibility to facilities and financial cost may not make it a viable option for most people with MS. An alternative approach for improving fitness is by increasing daily physical activity levels. The research team has developed and tested an Internet-delivered lifestyle physical activity intervention that has been shown to improve physical activity levels among people with MS. This lifestyle intervention is a promising approach for also increasing fitness and managing vascular comorbidity risk in persons with MS. This randomized clinical trial will examine the efficacy of a 6-month lifestyle physical activity intervention on cardiorespiratory fitness and vascular comorbidity risk in persons with MS.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.