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NCT03942718: SLEEP
Systemic Lupus Erythematosus Exercise Program
Completed
NA
Last updated 10 November 2022
What this trial tests
NA trial testing Exercise in Systemic Lupus Erythematosus in 30 participants. Completed in 1 August 2020.
Timeline
21 March 2018
Primary endpoint
25 April 2020
25 April 2020
1 August 2020
Quick facts
| Lead sponsor | University Medical Center Mainz |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 21 March 2018 |
| Primary completion | 25 April 2020 |
| Estimated completion | 1 August 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Exercise
Conditions studied
- Systemic Lupus Erythematosus — all drugs for Systemic Lupus Erythematosus →
Sponsor
University Medical Center Mainz
Who can join
Adults 18 to 65, any sex, with Systemic Lupus Erythematosus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot study is a randomized controlled trial to assess the effect of an individualized supervised exercise program in patients with systemic lupus erythematosus (SLE) compared to treatment-as-usual (TAU).
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA.
Pisareva E, Mihalovičová L, Pastor B, Kudriavtsev A, et al · · 2022 · cited 40× · PMID 36443816 · DOI 10.1186/s13073-022-01125-8 -
Validating quantitative PCR assays for cfDNA detection without DNA extraction in exercising SLE patients.
Neuberger EWI, Brahmer A, Ehlert T, Kluge K, et al · · 2021 · cited 24× · PMID 34193884 · DOI 10.1038/s41598-021-92826-4 -
Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial.
Boedecker SC, Philippi KFA, Neuberger E, Schmidt S, et al · · 2020 · cited 9× · PMID 33141101 · DOI 10.2196/18291 -
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA
Pisareva E, Mihalovičová L, Pastor B, Kudriavstev A, et al · · 2022 · cited 1× · DOI 10.1101/2022.09.01.506266
Verify or expand the search:
- PubMed search for NCT03942718
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other University Medical Center Mainz trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
Data sources for this page
- Trial protocol + status: ClinicalTrials.gov NCT03942718 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Center Mainz
- Last refreshed: 10 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03942718.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing