Last reviewed · How we verify
NCT03938870
CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease
trial testing L-Leucine 13C6 in Alzheimer's Disease in 96 participants. Completed in 6 July 2023.
6 July 2023
Quick facts
| Lead sponsor | Washington University School of Medicine |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 96 |
| Start date | 18 August 2015 |
| Primary completion | 6 July 2023 |
| Estimated completion | 6 July 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- L-Leucine 13C6
Conditions studied
- Alzheimer's Disease — all drugs for Alzheimer's Disease →
- Brain Diseases — all drugs for Brain Diseases →
- Central Nervous System Diseases — all drugs for Central Nervous System Diseases →
- Delirium, Dementia, Amnestic, Cognitive Disorders — all drugs for Delirium, Dementia, Amnestic, Cognitive Disorders →
Sponsor
Washington University School of Medicine
Who can join
18 and older, any sex, with Alzheimer's Disease or Brain Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Alzheimer's disease (AD) is the most common cause of dementia and currently has no disease modifying treatments or simple accurate diagnostic tests. The goal of this project is to study how tau (a protein thought to cause AD) is made, transported and cleared in the human body. Better understanding of these processes may lead to improved understanding of AD, earlier diagnosis and a way to evaluate treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03938870
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Washington University School of Medicine trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03938870 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
- Last refreshed: 13 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03938870.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing