Last reviewed · How we verify
NCT03934632
The Impact of Leg Immobilization on Postabsorptive and Postprandial Muscle Protein Breakdown in Healthy Young Males
NA trial testing Postabsorptive in Healthy in 24 participants. Completed in 9 January 2023.
17 March 2020
Quick facts
| Lead sponsor | University of Exeter |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 15 April 2019 |
| Primary completion | 17 March 2020 |
| Estimated completion | 9 January 2023 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Postabsorptive
- Postprandial
- Immobilisation
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
University of Exeter
Who can join
Adults 18 to 40, male only, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study will seek the quantify the simultaneous muscle protein synthesis and breakdown response with and without amino acid provision in humans following 2 days of immobilisation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Short-term disuse does not affect postabsorptive or postprandial muscle protein fractional breakdown rates.
Pavis GF, Abdelrahman DR, Murton AJ, Wall BT, et al · · 2023 · cited 16× · PMID 37431714 · DOI 10.1002/jcsm.13284
Verify or expand the search:
- PubMed search for NCT03934632
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Healthy
Currently open trials in the same condition.
- NCT06707207 — Predicting Future Errors During Skill Performance · recruiting
- NCT07169630 — PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) · Phase 1 · recruiting
- NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
- NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
- NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting
Other University of Exeter trials
Trials by the same sponsor.
- NCT07457437 — Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment · NA · recruiting
- NCT06478121 — Understanding Beta Cell Disorders Through the Study of Rare Genotypes (ENDURE) · recruiting
- NCT06965699 — The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults · NA · recruiting
- NCT06846294 — Obesity Prevention in Children and Young People Treated for Acute Lymphoblastic Leukaemia with ALLTogether · NA · not yet recruiting
- NCT06852547 — The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adu · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03934632 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Exeter
- Last refreshed: 22 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03934632.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing