NCT03934476 is a NA clinical trial of Ketogenic diet in Obesity, sponsored by University of Ostrava.

Who is sponsoring NCT03934476?

NCT03934476 is sponsored by University of Ostrava.

What drugs are being tested in NCT03934476?

Interventions in NCT03934476: Ketogenic diet, Exercise HIIT.

What condition does NCT03934476 study?

NCT03934476 studies Obesity, Diet Modification.

Is NCT03934476 still recruiting?

NCT03934476 is currently completed. Last updated 25 January 2021.

Last reviewed 2021-01-25 · How we verify

NCT03934476

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of Lowering Dietary Carbohydrates on Health, Exercise Performance and Wellbeing-related Outcomes

Completed NA Last updated 25 January 2021

What this trial tests

NA trial testing Ketogenic diet in Obesity in 100 participants. Completed in 31 December 2020.

Timeline

1 September 2018

Primary endpoint
31 December 2019

31 December 2020

Quick facts

Lead sponsor	University of Ostrava
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	100
Start date	1 September 2018
Primary completion	31 December 2019
Estimated completion	31 December 2020
Sites	1 location across Czechia

Drugs / interventions tested

Ketogenic diet — full drug profile →
Exercise HIIT

Conditions studied

Obesity — all drugs for Obesity →
Diet Modification — all drugs for Diet Modification →

Sponsor

University of Ostrava

Who can join

Adults 18 to 60, any sex, with Obesity or Diet Modification. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to investigate the long-term effects of the ketogenic diet and exercise (including interactions) on health markers, exercise performance and wellbeing outcomes in sedentary overweight individuals.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Very Low-Carbohydrate High-Fat Diet Improves Risk Markers for Cardiometabolic Health More Than Exercise in Men and Women With Overfat Constitution: Secondary Analysis of a Randomized Controlled Clinical Trial.
Cipryan L, Litschmannova M, Maffetone PB, Plews DJ, et al · · 2022 · cited 19× · PMID 35677551 · DOI 10.3389/fnut.2022.867690
A lipidomic and metabolomic signature of a very low-carbohydrate high-fat diet and high-intensity interval training: an additional analysis of a randomized controlled clinical trial.
Cipryan L, Kosek V, García CJ, Dostal T, et al · · 2023 · cited 14× · PMID 38141101 · DOI 10.1007/s11306-023-02071-1
Effects of a Very Low-Carbohydrate High-Fat Diet and High-Intensity Interval Training on Visceral Fat Deposition and Cardiorespiratory Fitness in Overfat Individuals: A Randomized Controlled Clinical Trial.
Cipryan L, Dostal T, Litschmannova M, Hofmann P, et al · · 2021 · cited 13× · PMID 34993222 · DOI 10.3389/fnut.2021.785694
Effect of very low-carbohydrate high-fat diet and high-intensity interval training on mental health-related indicators in individuals with excessive weight or obesity.
Sindler D, Dostal T, Litschmannova M, Hofmann P, et al · · 2024 · cited 1× · PMID 39543330 · DOI 10.1038/s41598-024-79378-z

Verify or expand the search:

Other trials of Ketogenic diet

Trials testing the same drug.

NCT07495267 — Nutritional Ketosis Marfan · NA · not yet recruiting
NCT07415590 — Ketogenic Diet for Post-Traumatic Stress Disorder (PTSD) · NA · not yet recruiting
NCT03991897 — Nutritional Ketosis: a Novel Metabolic Strategy to Treat Lymphedema Patients? · NA · recruiting
NCT07479095 — Low-glucose/High-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET/CT in Lepidic · NA · recruiting
NCT06963437 — Interventions for Weight Regain After Bariatric Surgery · NA · completed

Other recruiting trials for Obesity

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting

Other University of Ostrava trials

Trials by the same sponsor.

NCT07495241 — Prevalence of Carotid Web in Youth · recruiting
NCT05402280 — Sleep Disturbances and Delirium · NA · recruiting
NCT05637177 — Preventive Intervention to Promote Healthy Ageing · NA · completed
NCT05363852 — Questionnaire and Projective Color Association in Physiological Responses to Different Emotional Charge · NA · completed
NCT04669470 — Bariatric Endoscopy and NAFLD · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03934476 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Ostrava
Last refreshed: 25 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03934476.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing