NCT03934073: DEXTRAIN

Evaluation of the Benefit of the Training of the Manual Dexterity Post Stroke.

Completed NA Last updated 11 July 2024

What this trial tests

NA trial testing DEXTRAIN in Cerebral Vascular Accident in 126 participants. Completed in 27 April 2021.

Timeline

2 February 2018

Primary endpoint
31 August 2020

27 April 2021

Quick facts

Lead sponsor	Centre Hospitalier St Anne
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	126
Start date	2 February 2018
Primary completion	31 August 2020
Estimated completion	27 April 2021
Sites	1 location across France

Drugs / interventions tested

• DEXTRAIN
• CONVENTIONNELLE
• CONTROLE

Conditions studied

• Cerebral Vascular Accident — all drugs for Cerebral Vascular Accident →

Sponsor

Centre Hospitalier St Anne

Who can join

18 and older, any sex, with Cerebral Vascular Accident. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Stroke is the second leading cause of death and disability in France: more than half of stroke survivors have a disabling motor deficit, affecting mainly the upper limb. A lack of hand control makes everyday tasks more difficult and reduces the quality of life. The investigators lack approaches to specifically rehabilitate the hand after stroke.

Recently, a new tool has been developed to measure manual dexterity (the Finger Force Manipulandum or FFM). This tool, which records the forces applied by the fingers on pistons, allows to measure more finely the key components of manual dexterity during visuomotor tasks. The tool measures the ability to control and release the force applied by the fingers, to perform sequences, to track and maintain a frequency of tapping (temporality of movement) with the fingers, and to use the fingers independently one another.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Post-Stroke Impairments of Manual Dexterity and Finger Proprioception: Their Contribution to Upper Limb Activity Capacity.
   van Ravestyn C, Gerardin E, Térémetz M, Hamdoun S, et al · · 2024 · cited 8× · PMID 38572686 · DOI 10.1177/15459683241245416
2. Efficacy of interactive manual dexterity training after stroke: a pilot single-blinded randomized controlled trial.
   Térémetz M, Hamdoun S, Colle F, Gerardin E, et al · · 2023 · cited 6× · PMID 37464404 · DOI 10.1186/s12984-023-01213-9