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NCT03932552: LFN-EP
Effects of a Novel Physical Exercise Program in Patients With Cirrhosis (the LFN-exercise Protocol)
NA trial testing Exercise in Cirrhosis in 28 participants. Completed in 31 January 2020.
31 December 2019
Quick facts
| Lead sponsor | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 28 |
| Start date | 1 February 2016 |
| Primary completion | 31 December 2019 |
| Estimated completion | 31 January 2020 |
Drugs / interventions tested
- Exercise
- nutritional therapy
Conditions studied
- Cirrhosis — all drugs for Cirrhosis →
- Portal Hypertension — all drugs for Portal Hypertension →
- Exercise — all drugs for Exercise →
Sponsor
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran — full company profile →
Who can join
Adults 18 to 70, any sex, with Cirrhosis or Portal Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates the effects of a structured exercise (The LFN-exercise protocol) program plus diet, on cerebral hemodynamics (cerebral blood flow) and hepatic hemodynamics (portal pressure), as well as on nutritional status (body composition and nutritional markers) in order to facilitate the prescription of exercise in patients with cirrhosis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of a monitored exercise protocol in cerebral and hepatic hemodynamics in patients with cirrhosis and portal hypertension.
Macías-Rodríguez RU, Ruiz-Margáin A, Román-Calleja B, Cantú-Brito C, et al · · 2024 · cited 2× · PMID 38008698 · DOI 10.1016/j.dld.2023.11.011
Verify or expand the search:
- PubMed search for NCT03932552
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07589725 — Mulligan Mobilization in Lateral Elbow Tendinopathy · NA · not yet recruiting
- NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
- NCT06627569 — Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans · NA · not yet recruiting
Other recruiting trials for Cirrhosis
Currently open trials in the same condition.
- NCT07322237 — DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis · Phase 4 · recruiting
- NCT07521332 — Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis · Phase 4 · recruiting
- NCT07461545 — Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS · NA · recruiting
- NCT07461532 — Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD · NA · recruiting
- NCT07462091 — Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection · NA · recruiting
Other Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran trials
Trials by the same sponsor.
- NCT07004777 — Effect of Consuming n-3 Polyunsaturated Fatty Acids Rich Foods on Triglyceride Concentration and Lipoprotein Composition · NA · recruiting
- NCT07018622 — Protecting the Kidney's Proximal Tubules From Platinum-Based Chemotherapy Toxicity · Phase 2 · recruiting
- NCT07507981 — Effects of Exercise in Hemodialysis · NA · completed
- NCT06953193 — Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia · NA · recruiting
- NCT06556836 — "Diagnostic Accuracy of Ultrasound Compared to Epidurography for Epidural Catheter Localization" · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03932552 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Last refreshed: 1 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03932552.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing