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NCT03931486
Detection of Bacterial DNA and Collagen Metabolism in Acutely Ruptured Achilles Tendons
trial in Achilles Tendon Rupture in 20 participants. Completed in 1 April 2021.
1 April 2021
Quick facts
| Lead sponsor | Copenhagen University Hospital, Hvidovre |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 3 May 2019 |
| Primary completion | 1 April 2021 |
| Estimated completion | 1 April 2021 |
| Sites | 1 location across Denmark |
Conditions studied
- Achilles Tendon Rupture — all drugs for Achilles Tendon Rupture →
Sponsor
Copenhagen University Hospital, Hvidovre
Who can join
Adults 18 to 70, any sex, with Achilles Tendon Rupture. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The etiology and pathogenesis of acute Achilles tendon ruptures are complex and not fully understood. It is well known that they are associated with pre-existing pathological alterations, similar to the changes observed in tendinopathy. The present study investigates if bacteria and collagen metabolism play a role in the etiology of acute Achilles tendon rupture. During surgery, 20 patients will have taken two biopsies from the ruptured part of the tendon and two biopsies from the healthy tissue of the same tendon 2-4 cm proximal to the rupture, as a control.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Achilles Tendon Tissue Turnover Before and Immediately After an Acute Rupture.
Cramer A, Højfeldt G, Schjerling P, Agergaard J, et al · · 2023 · cited 7× · PMID 37313851 · DOI 10.1177/03635465231177890
Verify or expand the search:
- PubMed search for NCT03931486
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Achilles Tendon Rupture
Currently open trials in the same condition.
- NCT07498166 — Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupt · NA · active not recruiting
- NCT07453485 — Immediate Effects of Neuromuscular Electrical Stimulation on Pain and Function in Achilles Tendon Disorders · NA · recruiting
- NCT07130357 — The Effect of Collagen Scaffold Augmentation in Achilles Tendon Rupture Repair · NA · recruiting
- NCT06723639 — Restoring Anatomy of Ruptured Achilles Tendon · NA · recruiting
- NCT06434272 — Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture · NA · recruiting
Other Copenhagen University Hospital, Hvidovre trials
Trials by the same sponsor.
- NCT07321379 — Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour · NA · not yet recruiting
- NCT07067060 — Risk of Serious Adverse Events Following Unsupervised vs Supervised Rehabilitation After Knee Arthroplasty · not yet recruiting
- NCT06967324 — GRACE - Graduated Response for Advanced COPD With Enhanced Support · NA · recruiting
- NCT06682260 — Evaluating the Effects of Nitroglycerin on Heart Function and Urinary Output in Patients With Acute Heart Failure · Phase 4 · completed
- NCT06866496 — Optimized Remission in Alcohol-related Liver Cirrhosis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03931486 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Copenhagen University Hospital, Hvidovre
- Last refreshed: 29 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03931486.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing